[HTML][HTML] Melittin prevents metastasis of epidermal growth factor-induced MDA-MB-231 cells through the inhibition of the SDF-1α/CXCR4 signaling pathway

F Salimian, M Nabiuni, E Salehghamari - Cell Journal (Yakhteh), 2022 - ncbi.nlm.nih.gov
Objective Melittin is one of the natural components of bee venom (Apis mellifera), and its
anticancer and antimetastatic properties have been well established, but the underlying …

Molecular imaging in multiple myeloma—novel PET radiotracers improve patient management and guide therapy

J von Hinten, M Kircher, A Dierks, CH Pfob… - Frontiers in Nuclear …, 2022 - frontiersin.org
Due to its proven value in imaging of multiple myeloma (MM), including staging,
prognostication, and assessment of therapy response, 2-deoxy-2-[18F] fluoro-D-glucose …

C-terminal–modified LY2510924: a versatile scaffold for targeting CXC chemokine receptor type 4

K Suzuki, T Ui, A Nagano, A Hino, Y Arano - Scientific Reports, 2019 - nature.com
CXC chemokine receptor type 4 (CXCR4) constitutes a promising target for tumor diagnosis
and therapy. Herein, we evaluate a new 1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10 …

[68 Ga] Ga-CXCR4 PET/CT imaging in high-grade glioma for assessment of CXCR4 receptor expression

H Roustaei, H Vosoughi, E Askari, BA Kalantari… - European Journal of …, 2024 - Elsevier
Purpose Gliomas account for 75% of primary malignant CNS tumors. High-grade glioma
(CNS WHO grades 3 and 4) have an unfavorable treatment response and poor outcome …

Chemokine Receptor 4-Targeted PET/CT with [68Ga]pentixather in Newly Diagnosed Multiple Myeloma: a Comparative Study with [68Ga]pentixafor PET/CT

Q Yang, F Zhang, Z Hao, J Zhuang, L Huo - Molecular Imaging and …, 2024 - Springer
Purpose This study aimed to compare the detection rate of [68Ga] pentixather PET/CT and
[68Ga] pentixafor PET/CT in newly diagnosed multiple myeloma (NDMM) patients, and to …

New PET Tracers for Lymphoma

JS Enke, RA Bundschuh, R Claus, C Lapa - PET clinics, 2024 - pet.theclinics.com
Background Functional imaging with 2-[fluorine 18] fluoro-2-deoxy-d-glucose (FDG) positron
emission tomography (PET)/computed tomography (CT) plays a crucial role in lymphoma …

Multivalency in CXCR4 chemokine receptor targeted iron oxide nanoparticles

NE Baghdadi, BP Burke, T Alresheedi, S Nigam… - Dalton …, 2021 - pubs.rsc.org
The CXCR4 chemokine receptor is an important biomolecular target in cancer diagnostics
and therapeutics. In a new multivalent approach, iron oxide nanoparticles were conjugated …

State-of-the-art modalities in cardio-oncology: Insight from a nuclear medicine approach

N Jokar, A Amini, M Ravanbod… - Nuclear Medicine …, 2021 - journals.viamedica.pl
Cancer and cardiovascular disease are the most significant causes of morbidity and
mortality worldwide. Although the cancer survival rate has increased due to improved …

The emerging role of cell surface receptor and protein binding radiopharmaceuticals in cancer diagnostics and therapy

L Aloj, B Attili, D Lau, C Caraco, LM Lechermann… - Nuclear Medicine and …, 2021 - Elsevier
Targeting specific cell membrane markers for both diagnostic imaging and radionuclide
therapy is a rapidly evolving field in cancer research. Some of these applications have now …

PET imaging in dementia: Mini-review and Canadian perspective for clinical use

F Juengling, F Wuest, R Schirrmacher… - Canadian Journal of …, 2024 - cambridge.org
PET imaging is increasingly recognized as an important diagnostic tool to investigate
patients with 25 cognitive disturbances of possible neurodegenerative origin. PET with 2 …