Detecting RNA modifications in the epitranscriptome: predict and validate

M Helm, Y Motorin - Nature Reviews Genetics, 2017 - nature.com
RNA modifications are emerging players in the field of post-transcriptional regulation of
gene expression, and are attracting a comparable degree of research interest to DNA and …

Modern epigenetics methods in biological research

Y Li - Methods, 2021 - Elsevier
The definition of epigenetics refers that molecular modifications on DNA that can regulate
gene activity are independent of DNA sequence and mitotically stable. Notably, epigenetics …

DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …

DNA methylation profiling in the clinic: applications and challenges

H Heyn, M Esteller - Nature Reviews Genetics, 2012 - nature.com
Abstract Knowledge of epigenetic alterations in disease is rapidly increasing owing to the
development of genome-wide techniques for their identification. The ever-growing number …

Marine environmental epigenetics

JM Eirin-Lopez, HM Putnam - Annual review of marine science, 2019 - annualreviews.org
Marine organisms' persistence hinges on the capacity for acclimatization and adaptation to
the myriad of interacting environmental stressors associated with global climate change. In …

Principles and challenges of genome-wide DNA methylation analysis

PW Laird - Nature Reviews Genetics, 2010 - nature.com
Methylation of cytosine bases in DNA provides a layer of epigenetic control in many
eukaryotes that has important implications for normal biology and disease. Therefore …

[HTML][HTML] Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals

BR Carone, L Fauquier, N Habib, JM Shea, CE Hart… - Cell, 2010 - cell.com
Epigenetic information can be inherited through the mammalian germline and represents a
plausible transgenerational carrier of environmental information. To test whether …

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications

RA Harris, T Wang, C Coarfa, RP Nagarajan… - Nature …, 2010 - nature.com
Abstract Analysis of DNA methylation patterns relies increasingly on sequencing-based
profiling methods. The four most frequently used sequencing-based technologies are the …

DNA methylome analysis using short bisulfite sequencing data

F Krueger, B Kreck, A Franke, SR Andrews - Nature methods, 2012 - nature.com
Bisulfite conversion of genomic DNA combined with next-generation sequencing (BS-seq) is
widely used to measure the methylation state of a whole genome, the methylome, at single …

Lamarck rises from his grave: parental environment‐induced epigenetic inheritance in model organisms and humans

Y Wang, H Liu, Z Sun - Biological Reviews, 2017 - Wiley Online Library
Organisms can change their physiological/behavioural traits to adapt and survive in
changed environments. However, whether these acquired traits can be inherited across …