Advances in biological therapies for dyslipidemias and atherosclerosis
EK Valanti, K Dalakoura-Karagkouni, G Siasos… - Metabolism, 2021 - Elsevier
Atherosclerosis is a multifactorial disease influenced by genetics, lifestyle and
environmental factors. Despite therapeutic advances that reduce the risk of cardiovascular …
environmental factors. Despite therapeutic advances that reduce the risk of cardiovascular …
HDL in the 21st century: a multifunctional roadmap for future HDL research
A Rohatgi, M Westerterp, A Von Eckardstein… - Circulation, 2021 - Am Heart Assoc
Low high-density lipoprotein cholesterol (HDL-C) characterizes an atherogenic dyslipidemia
that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular …
that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular …
Apolipoprotein mimetic peptides: potential new therapies for cardiovascular diseases
Since the seminal breakthrough of treating diabetic patients with insulin in the 1920s, there
has been great interest in developing other proteins and their peptide mimetics as therapies …
has been great interest in developing other proteins and their peptide mimetics as therapies …
[HTML][HTML] Apolipoproteins as potential communicators play an essential role in the pathogenesis and treatment of early atherosclerosis
Y Li, X Luo, Z Hua, X Xue, X Wang, M Pang… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Atherosclerosis as the leading cause of the cardiovascular disease is closely related to
cholesterol deposition within subendothelial areas of the arteries. Significantly, early …
cholesterol deposition within subendothelial areas of the arteries. Significantly, early …
Reconstituted HDL-apoE3 promotes endothelial cell migration through ID1 and its downstream kinases ERK1/2, AKT and p38 MAPK
EK Valanti, K Dalakoura-Karagkouni, P Fotakis… - Metabolism, 2022 - Elsevier
Abstract Introduction Atherosclerotic Coronary Artery Disease (ASCAD) is the leading cause
of mortality worldwide. Novel therapeutic approaches aiming to improve the atheroprotective …
of mortality worldwide. Novel therapeutic approaches aiming to improve the atheroprotective …
Apolipoprotein and LRP1-based peptides as new therapeutic tools in atherosclerosis
A Benitez Amaro, A Solanelles Curco, E Garcia… - Journal of clinical …, 2021 - mdpi.com
Apolipoprotein (Apo)-based mimetic peptides have been shown to reduce atherosclerosis.
Most of the ApoC-II and ApoE mimetics exert anti-atherosclerotic effects by improving lipid …
Most of the ApoC-II and ApoE mimetics exert anti-atherosclerotic effects by improving lipid …
[HTML][HTML] Hepatic paraoxonase 1 ameliorates dysfunctional high-density lipoprotein and atherosclerosis in scavenger receptor class B type I deficient mice
XJ Zhao, LC Liu, C Guo, WW Shen, J Cao… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background: High-density lipoprotein (HDL) plays an antiatherogenic role by mediating
reverse cholesterol transport (RCT), antioxidation, anti-inflammation, and endothelial cell …
reverse cholesterol transport (RCT), antioxidation, anti-inflammation, and endothelial cell …
Apolipoprotein A-IV and its derived peptide, T55− 121, improve glycemic control and increase energy expenditure
It is crucial to understand the glucose control within our bodies. Bariatric/metabolic
surgeries, including laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass …
surgeries, including laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass …
Simultaneous quantification of apolipoproteins AI, E, and J in human plasma by LC-MS/MS for clinical application to diabetes mellitus complicated with cardiovascular …
P Li, Y Cong, W Zhang, L Wang, L Ren, X Li, S Yang… - RSC …, 2022 - pubs.rsc.org
Apolipoproteins (Apos) play an important role in regulating plasma lipid concentration.
Complex disorders of Apos are highly related with diabetes mellitus, cardiovascular and …
Complex disorders of Apos are highly related with diabetes mellitus, cardiovascular and …
Global research trends of Apolipoprotein E in central nervous system: A scientometric analysis
K Gong, Y Chen, W Liu, Z Wang - International Immunopharmacology, 2021 - Elsevier
Abstract Apolipoprotein E (apoE, protein; APOE, gene) involves in cholesterol recycling and
redistribution by mediating lipoprotein pathways unique to central nervous system (CNS) …
redistribution by mediating lipoprotein pathways unique to central nervous system (CNS) …