The pro-inflammatory immune response driven by microglia is a key contributor to the
pathogenesis of several neurodegenerative diseases. Though the research of microglia …

One of the most striking hallmarks shared by various neurodegenerative diseases, including
Parkinson's disease, Alzheimer's disease (AD), and amyotrophic lateral sclerosis, is …

Polyamines are essential for the proliferation, differentiation, and development of
eukaryotes. They include spermine, spermidine, and the diamine precursor putrescine, and …

The immune response in the brain has been widely investigated and while many studies
have focused on the proinflammatory cytotoxic response, the brain's innate immune system …

Polyamines (PAs) are ubiquitous biogenic amines that have been implicated in diverse
cellular functions in widely distributed organisms. In plants, mutant and transgenic plants …

The essential amino acid, methionine, is important for cancer cell growth and metabolism. A
growing body of evidence indicates that methionine restriction inhibits cancer cell growth …

Polyamines are low molecular weight, aliphatic polycations found in the cells of all living
organisms. Due to their positive charges, polyamines bind to macromolecules such as DNA …

Root canal therapy has been practiced ever since 1928 and the success rate has
tremendously increased over the years owing to various advancements in the field. One …

Abstract G-quadruplex (G4) is a non-canonical structure that is formed in G-rich sequences
of nucleic acids. G4s play important roles in vivo, such as telomere maintenance …

Polyamines are essential for the growth and function of normal cells. They interact with
various macromolecules, both electrostatically and covalently and, as a consequence, have …