Scleroderma is a multisystem autoimmune disease characterized by an abnormal immune
activation associated with the development of underlying vascular and fibrotic disease …

BACKGROUND. In patients with limited response to conventional therapeutics, repositioning
of already approved drugs can bring new, more effective options. Current drug repositioning …

Objective. To investigate the rate, type, characteristics, and predictors of infection in a cohort
of patients with psoriatic arthritis (PsA) and a cohort of patients with psoriasis without arthritis …

Inflammatory bowel diseases (IBDs) are chronic disorders resulting from abnormal and
persistent immune responses which lead to severe tissue injury and disturbances in …

In light of the risk of hepatosplenic T-cell lymphomas, a greater degree of caution is
warranted in the use of azathioprine. NBUVB, mycophenolate, and methotrexate remain the …

Objective: To understand the mechanism by which (-)-epigallocatechin-3-gallate (EGCG),
the major polyphenol of green tea, exerts its anti-inflammatory action. Methods: To check our …

OBJECTIVE: Methylxanthines, like caffeine, have been thought to reverse the
antiinflammatory effects of methotrexate (MTX) in rheumatoid arthritis (RA). We investigated …

Background Safety of the combination of leflunomide and methotrexate was examined in
several studies with inconclusive results. The present study was designed to compare the …

Background Haploidentical stem cell transplantation (haplo‐SCT) is an option for patients
without human leukocyte antigen‐matched related or unrelated donor. Post-transplantation …

Apoptosis is an inducible suicide program that occurs in all phases of multicellular as well as
in protozoa life and gains more and more importance in all medical disciplines. It is required …