The diverse host defense and immunoregulatory functions of human T cells are performed
by phenotypically heterogeneous subpopulations. Among the membrane antigens that are …

The leucocyte-common antigen is a family of surface glycoproteins that are expressed in a
cell-type-specific fashion. Here, Matthew Thomas and Leo Lefrançois review recent …

Various protocols were developed and compared for eliciting specific cytotoxic T lymphocyte
(CTL) cell lines from the unselected human peripheral blood mononuclear cells of naive …

Leukocyte common antigens (LCAs, also known as T200 and CD 45) are integral
membrane proteins expressed exclusively on hematopoietic cells. These molecules exhibit …

Using limiting dilution analysis, we investigated proliferative responses of UCHL1+ and
UCHL1− T cell populations to compare the precursor cell frequencies following recall and …

Three independent mutations involving the apoptosis-1 (APO-1)/Fas receptor or its putative
ligand have led to lupuslike diseases associated with lymphadenopathy in different strains …

Several T-cell structures are capable of generating intracellular signals linked to T-cell
proliferation. Crosslinking of CD2, CD4 and CD45 with Ti/CD3 to several of these antigens …

Upregulation of integrin adhesive receptors has been implicated in various pathological
conditions. We examined expression and function of integrin adhesive receptors on …

The lentiviruses of sheep, goats, and horses cause chronic multiorgan disease in which
macrophages are highly permissive for viral replication. Monocytes, which mature into …

On the basis of differential CD45 expression, human T cells can be separated into
approximately reciprocal populations. The mAb UCHL1 detects a 180 kd molecular mass …