Control of host mitochondria by bacterial pathogens
Mitochondria control various processes that are integral to cellular and organismal
homeostasis, including Ca 2+ fluxes, bioenergetic metabolism, and cell death. Perhaps not …
homeostasis, including Ca 2+ fluxes, bioenergetic metabolism, and cell death. Perhaps not …
[HTML][HTML] Pgp3 protein of Chlamydia trachomatis inhibits apoptosis via HO-1 upregulation mediated by PI3K/Akt activation
M Shu, J Bu, W Lei, L Chen, Z Zhou, C Lu, C Chen… - Microbial …, 2023 - Elsevier
As an obligate intracellular pathogen, Chlamydia trachomatis assumes various strategies to
inhibit host cells apoptosis, thereby providing a suitable intracellular environment to ensure …
inhibit host cells apoptosis, thereby providing a suitable intracellular environment to ensure …
Chlamydia Infection Remodels Host Cell Mitochondria to Alter Energy Metabolism and Subvert Apoptosis
Chlamydia infection represents an important cause for concern for public health worldwide.
Chlamydial infection of the genital tract in females is mostly asymptomatic at the early stage …
Chlamydial infection of the genital tract in females is mostly asymptomatic at the early stage …
Chlamydia trachomatis Pgp3 protein regulates oxidative stress via activation of the Nrf2/NQO1 signal pathway
M Shu, W Lei, S Su, Y Wen, F Luo, L Zhao, L Chen… - Life Sciences, 2021 - Elsevier
Aim Chlamydia trachomatis has evolved various strategies to alleviate oxidative stress of
host cells to maintain their intracellular survival. However, the exact mechanism of anti …
host cells to maintain their intracellular survival. However, the exact mechanism of anti …
Chlamydia trachomatis Plasmid Protein pORF5 Up-Regulates ZFAS1 to Promote Host Cell Survival via MAPK/p38 Pathway
Y Wen, H Chen, F Luo, L Zhao, M Shu, S Su… - Frontiers in …, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) have been demonstrated to play essential roles in many
diseases. However, few studies have shown that lncRNAs take part in the pathogenesis of …
diseases. However, few studies have shown that lncRNAs take part in the pathogenesis of …
Antiapoptotic activity of Chlamydia trachomatis Pgp3 protein involves activation of the ERK1/2 pathway mediated by upregulation of DJ-1 protein
F Luo, M Shu, S Gong, Y Wen, B He… - Pathogens and …, 2019 - academic.oup.com
Chlamydia trachomatis has evolved strategies to prevent host cell apoptosis to evade the
host immune defense. However, the precise mechanisms of antiapoptotic activity of C …
host immune defense. However, the precise mechanisms of antiapoptotic activity of C …
Chlamydia trachomatis induces lncRNA MIAT upregulation to regulate mitochondria‐mediated host cell apoptosis and chlamydial development
F Luo, Y Wen, L Zhao, S Su, Y Zhao… - Journal of cellular and …, 2022 - Wiley Online Library
Chlamydia trachomatis persistent infection is the leading cause of male prostatitis and
female genital tract diseases. Inhibition of host cell apoptosis is the key to maintaining …
female genital tract diseases. Inhibition of host cell apoptosis is the key to maintaining …
Chlamydia trachomatis plasmid-encoded protein pORF5 activates unfolded protein response to induce autophagy via MAPK/ERK signaling pathway
Y Wen, F Luo, Y Zhao, S Su, M Shu, Z Li - Biochemical and biophysical …, 2020 - Elsevier
Chlamydia trachomatis (C. trachomatis) is an obligate intracellular organism that depends
on nutrients from the host cell for their replication and proliferation. Therefore, the interaction …
on nutrients from the host cell for their replication and proliferation. Therefore, the interaction …
Bacteria exploit autophagy for their own benefit
Q Xiong, M Yang, P Li, C Wu - Infection and Drug Resistance, 2019 - Taylor & Francis
Autophagy is a lysosomal degradation pathway to clear long-lived proteins, protein
aggregates, and damaged organelles. Certain microorganisms can be eliminated by an …
aggregates, and damaged organelles. Certain microorganisms can be eliminated by an …
TLR2 mediates autophagy through ERK signaling pathway in Chlamydia psittaci CPSIT_p7 protein‐stimulated RAW264.7 cells
Y Luo, Z Sun, Q Chen, J Xiao, XL Yan… - Microbiology and …, 2023 - Wiley Online Library
Chlamydia psittaci is a zoonotic pathogen found in birds and humans. Macrophages, major
components of the innate immune system, can resist chlamydial infections and trigger …
components of the innate immune system, can resist chlamydial infections and trigger …