Background Patients with muscle-invasive bladder cancer face a poor prognosis due to
rapid disease progression and chemoresistance. Thus, there is an urgent need for a new …

Tumor cells without mitochondrial (mt) DNA (ρ0 cells) are auxotrophic for uridine, and their
growth is supported by pyruvate. While ATP synthesis in ρ0 cells relies on glycolysis, they …

Background Polygonum multiflorum (PM) is a core herb that enhances immunity. It can also
detoxify, reduce swelling, and intercept malaria. Its main components, emodin (EMD) and 2 …

Background: Complement component 1 Q subcomponent binding protein (C1QBP) plays a
vital role in the progression and metabolism of cancer. Studies have shown that xanthine …

The effectiveness of chemotherapy and radiotherapy to treat lung cancer is limited because
of highly metastatic nature. Novel strategies and drugs to attenuate metastatic activity are …

Background Triple-negative breast cancer (TNBC) accounts for 20% of breast cancer that
does not express HER2, progesterone and estrogen receptors. It is associated with a high …

Although the tumor microenvironment (TME) plays an important role in the development of
many cancers, its roles in breast cancer, especially triple-negative breast cancer (TNBC) …

Immunotherapy represents an attractive avenue for cancer therapy due to its tumour
specificity and relatively low frequency of adverse effects compared to other treatment …

Background/Aim: New anticancer drugs are usually tested on cancer cells in culture in a
standard medium. We stimulated immune polynuclear cells by lipopolysaccharides to obtain …

The expression and function of many ion channels and transporters in cancer cells display
major differences in comparison to those from healthy cells. These differences provide the …