[HTML][HTML] Diagnosis and treatment of basal cell carcinoma: European consensus–based interdisciplinary guidelines

K Peris, MC Fargnoli, C Garbe, R Kaufmann… - European Journal of …, 2019 - Elsevier
Basal cell carcinoma (BCC) is the most common malignant tumour in white populations.
Multidisciplinary experts from the European Dermatology Forum, the European Association …

[HTML][HTML] Non-melanoma skin cancers: Biological and clinical features

M Cives, F Mannavola, L Lospalluti, MC Sergi… - International Journal of …, 2020 - mdpi.com
Non-melanoma skin cancers (NMSCs) include basal cell carcinoma (BCC), squamous cell
carcinoma (SCC) and Merkel cell carcinoma (MCC). These neoplasms are highly diverse in …

[HTML][HTML] Basal cell carcinoma: from pathophysiology to novel therapeutic approaches

L Fania, D Didona, R Morese, I Campana, V Coco… - Biomedicines, 2020 - mdpi.com
Basal cell carcinoma (BCC) is the most common human cancer worldwide, and is a subtype
of nonmelanoma skin cancer, characterized by a constantly increasing incidence due to an …

Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind …

MR Migden, A Guminski, R Gutzmer, L Dirix… - The Lancet …, 2015 - thelancet.com
Background Patients with advanced basal cell carcinoma have limited treatment options.
Hedgehog pathway signalling is aberrantly activated in around 95% of tumours. We …

[HTML][HTML] Skin cancer epidemics in the elderly as an emerging issue in geriatric oncology

S Garcovich, G Colloca, P Sollena, B Andrea… - Aging and …, 2017 - ncbi.nlm.nih.gov
Skin cancer is a worldwide, emerging clinical need in the elderly white population, with a
steady increase in incidence rates, morbidity and related medical costs. Skin cancer is a …

Sonidegib and vismodegib in the treatment of patients with locally advanced basal cell carcinoma: a joint expert opinion

R Dummer, PA Ascierto… - Journal of the …, 2020 - Wiley Online Library
Sonidegib and vismodegib are hedgehog pathway inhibitors (HhIs) approved for the
treatment of advanced basal cell carcinoma (BCC). Until recently, vismodegib was the only …

[HTML][HTML] Update on the management of basal cell carcinoma

N Basset-Seguin, F Herms - Acta Dermato-Venereologica, 2020 - ncbi.nlm.nih.gov
Basal cell carcinomas are the most frequent skin cancers in the fair-skinned adult population
over 50 years of age. Their incidence is increasing throughout the world. Ultraviolet (UV) …

[HTML][HTML] The 12-month analysis from Basal Cell Carcinoma Outcomes with LDE225 Treatment (BOLT): a phase II, randomized, double-blind study of sonidegib in …

R Dummer, A Guminski, R Gutzmer, L Dirix… - Journal of the American …, 2016 - Elsevier
Background The hedgehog pathway inhibitor sonidegib demonstrated meaningful tumor
shrinkage in more than 90% of patients with locally advanced basal cell carcinoma (BCC) or …

[HTML][HTML] Five-year results of a randomized controlled trial comparing effectiveness of photodynamic therapy, topical imiquimod, and topical 5-fluorouracil in patients …

MHE Jansen, K Mosterd, AHMM Arits… - Journal of Investigative …, 2018 - Elsevier
For the treatment of superficial basal cell carcinoma, a prospective, noninferiority,
randomized controlled multicenter trial with 601 patients showed that 5% imiquimod cream …

Minimum standards on prevention, diagnosis and treatment of occupational and work‐related skin diseases in Europe–position paper of the COST Action StanDerm …

JH Alfonso, A Bauer, L Bensefa‐Colas… - Journal of the …, 2017 - Wiley Online Library
Background Skin diseases constitute up to 40% of all notified occupational diseases in most
European countries, predominantly comprising contact dermatitis, contact urticaria, and skin …