Cancer immunotherapy holds great potential to battle cancer by exerting a durable immunity
effect. However, this process might be limited by various constraints existing in the tumor …

Complex pathological diseases, such as cancer, infection, and Alzheimer's, need to be
targeted by multipronged curative. Various omics technologies, with a high rate of data …

In 2019, the world faced a serious health challenge, the rapid spreading of a life-threatening
viral pneumonia, coronavirus disease 2019 (COVID-19) caused by a betacoronavirus …

Purpose Cardiovascular disease (CVD) is the leading cause of death, globally, and its
prevalence is only expected to rise due to the increasing incidence of co-morbidities such as …

Background and aim Gut microbiota (GM) can support colorectal cancer (CRC) progression
by modulating immune responses through the production of both immunostimulatory and/or …

Cancer is a primary cause of human fatality and conventional cancer therapies, eg,
chemotherapy, are often associated with adverse side-effects, tumor drug-resistance, and …

N‐glycosylation is critical for recombinant glycoprotein production as it influences the
heterogeneity of products and affects their biological function. In most eukaryotes, the …

Since cancer cells often evade apoptosis, induction of necroptosis as another mode of
programmed cell death is considered a promising therapeutic alternative. Here, we identify a …

Norovirus represents the main cause of acute nonbacterial gastroenteritis worldwide. In
immunocompromised patients, it bears high risk of causing chronic infection with significant …

Most of the recent approved therapeutic proteins are multi-subunit biologics, which need
glycosylation and disulfide bridges for their correct conformation and biological functions …