The neuroprotective potentiality of flavonoids on Alzheimer's disease

A Calderaro, GT Patanè, E Tellone, D Barreca… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD), due to its spread, has become a global health priority, and is
characterized by senile dementia and progressive disability. The main cause of AD and …

Flavonoids: structure–function and mechanisms of action and opportunities for drug development

S Safe, A Jayaraman, RS Chapkin, M Howard… - Toxicological …, 2021 - Springer
Flavonoids are polyphenolic phytochemicals produced in fruits, nuts and vegetables and
dietary consumption of these structurally diverse compounds is associated with multiple …

The human milk component myo-inositol promotes neuronal connectivity

AF Paquette, BE Carbone, S Vogel… - Proceedings of the …, 2023 - National Acad Sciences
Effects of micronutrients on brain connectivity are incompletely understood. Analyzing
human milk samples across global populations, we identified the carbocyclic sugar myo …

Long-term dietary flavonoid intake and subjective cognitive decline in US men and women

TS Yeh, C Yuan, A Ascherio, BA Rosner, WC Willett… - Neurology, 2021 - AAN Enterprises
Objective To prospectively examine the associations between long-term dietary flavonoids
and subjective cognitive decline (SCD). Methods We followed 49,493 women from the …

Flavonoids and mitochondria: activation of cytoprotective pathways?

A Kicinska, W Jarmuszkiewicz - Molecules, 2020 - mdpi.com
A large number of diverse mechanisms that lead to cytoprotection have been described to
date. Perhaps, not surprisingly, the role of mitochondria in these phenomena is notable. In …

Protective effects of anthocyanins on neurodegenerative diseases

P Li, D Feng, D Yang, X Li, J Sun, G Wang… - Trends in Food Science …, 2021 - Elsevier
The neurodegenerative disease is a vital threat to the elders, the incidence is increasing but
the efficient therapy is rare. A feasible strategy to treat neurodegenerative diseases is dietary …

[HTML][HTML] Healthy aging—nutrition matters: start early and screen often

SB Roberts, RE Silver, SK Das, RA Fielding… - Advances in …, 2021 - Elsevier
The amount of time spent in poor health at the end of life is increasing. This narrative review
summarizes consistent evidence indicating that healthy dietary patterns and maintenance of …

Naringenin: A prospective therapeutic agent for Alzheimer's and Parkinson's disease

A Goyal, A Verma, N Dubey, J Raghav… - Journal of Food …, 2022 - Wiley Online Library
Neurodegenerative disorders (NDs) are a cluster of progressive, severe, and disabling
disorders that affect millions of people worldwide and are on the surge. These disorders are …

Effects of a mediterranean diet on the gut microbiota and microbial metabolites: A systematic review of randomized controlled trials and observational studies

R Kimble, P Gouinguenet, A Ashor… - Critical Reviews in …, 2023 - Taylor & Francis
Consumption of the Mediterranean dietary pattern (MedDiet) is associated with reduced risk
of numerous non-communicable diseases. Modulation of the composition and metabolism of …

Brain-derived neurotrophic factor signaling in the pathophysiology of Alzheimer's disease: Beneficial effects of flavonoids for neuroprotection

T Numakawa, H Odaka - International Journal of Molecular Sciences, 2021 - mdpi.com
The function of the brain-derived neurotrophic factor (BDNF) via activation through its high-
affinity receptor Tropomyosin receptor kinase B (TrkB) has a pivotal role in cell …