The increased metabolic activity of the heart as a pump involves a high demand of
mitochondrial adenosine triphosphate (ATP) production for its mechanical and electrical …

Abstract Two decades ago, Kidney Disease: Improving Global Outcomes coined the term
chronic kidney disease–mineral and bone disorder (CKD–MBD) to describe the syndrome of …

Aims Vascular calcification (VC) is prevalent in pathological processes such as diabetes,
chronic kidney disease (CKD), and atherosclerosis, but effective therapies are still lacking by …

Medial arterial calcification (MAC), a systemic vascular disease different from
atherosclerosis, is associated with an increased incidence of cardiovascular events. Several …

Vascular calcification is an important risk factor for cardiovascular events, accompanied by
DNA damage during the process. The sirtuin 6 (SIRT6) has been reported to alleviate …

Emerging evidence indicates that alteration of gut microbiota plays an important role in
chronic kidney disease (CKD)-related vascular calcification (VC). We aimed to investigate …

Vascular calcification (VC) is a consequence of chronic kidney disease (CKD) which is of
paramount importance regarding the survival of CKD patients. VC is far from being …

Background Ischemic stroke (IS) is a major cause of mortality and disability worldwide.
Inflammatory response is crucial in the pathogenesis of tissue injury in cerebral infarction …

Vascular calcification (VC) is highly prevalent and increases the morbidity and mortality of
cardiovascular diseases. However, the underlying mechanism remains unclear and there is …

Vascular calcification (VC) is an accurate risk factor and predictor of adverse cardiovascular
events; however, there is currently no effective therapy to specifically prevent VC …