Proton and Carbon Ion Irradiation Changes the Process of Endochondral Ossification in an Ex Vivo Femur Organotypic Culture Model

V Etschmaier, D Glänzer, N Eck, U Schäfer, A Leithner… - Cells, 2023 - mdpi.com
Particle therapy (PT) that utilizes protons and carbon ions offers a promising way to reduce
the side effects of radiation oncology, especially in pediatric patients. To investigate the …

[HTML][HTML] Total body irradiation is associated with long-term deficits in femoral bone structure but not mechanical properties in male rhesus macaques

IR Barnet, SR Emerzian, R Behzad, DJ Brooks… - Scientific Reports, 2024 - nature.com
Exposure to ionizing radiation for oncological therapy increases the risk for late-onset
fractures in survivors. However, the effects of total body irradiation (TBI) on adult bone are …

Radiation-induced changes in load-sharing and structure-function behavior in murine lumbar vertebrae

T Wu, NB Bonnheim, MM Pendleton… - Computer Methods in …, 2024 - Taylor & Francis
In this study, we used micro-CT-based finite element analysis to investigate the
biomechanical effects of radiation on the microstructure and mechanical function of murine …