Prevention of acute exacerbations of COPD: American college of chest physicians and Canadian thoracic society guideline

GJ Criner, J Bourbeau, RL Diekemper, DR Ouellette… - Chest, 2015 - Elsevier
BACKGROUND: COPD is a major cause of morbidity and mortality in the United States as
well as throughout the rest of the world. An exacerbation of COPD (periodic escalations of …

New anti-inflammatory targets for chronic obstructive pulmonary disease

PJ Barnes - Nature reviews Drug discovery, 2013 - nature.com
Chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation of
the peripheral airways and lung parenchyma, which leads to progressive obstruction of the …

Pharmacology and therapeutics of bronchodilators

M Cazzola, CP Page, L Calzetta, MG Matera - Pharmacological Reviews, 2012 - ASPET
Bronchodilators are central in the treatment of of airways disorders. They are the mainstay of
the current management of chronic obstructive pulmonary disease (COPD) and are critical in …

β2-Agonist Therapy in Lung Disease

M Cazzola, CP Page, P Rogliani… - American journal of …, 2013 - atsjournals.org
β2-Agonists are effective bronchodilators due primarily to their ability to relax airway smooth
muscle (ASM). They exert their effects via their binding to the active site of β2-adrenoceptors …

Therapeutic approaches to asthma–chronic obstructive pulmonary disease overlap syndromes

PJ Barnes - Journal of Allergy and Clinical Immunology, 2015 - Elsevier
The recognition that there are some patients with features of asthma and chronic obstructive
pulmonary disease (COPD) has highlighted the need to develop more specific treatments for …

PLGA-based micro/nanoparticles: an overview of their applications in respiratory diseases

X Guo, X Zuo, Z Zhou, Y Gu, H Zheng, X Wang… - International Journal of …, 2023 - mdpi.com
Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD),
are critical areas of medical research, as millions of people are affected worldwide. In fact …

Combination bronchodilator therapy in the management of chronic obstructive pulmonary disease

DP Tashkin, GT Ferguson - Respiratory research, 2013 - Springer
Chronic obstructive pulmonary disease (COPD) represents a significant cause of global
morbidity and mortality, with a substantial economic impact. Recent changes in the Global …

Lung macrophage functional properties in chronic obstructive pulmonary disease

K Akata, SF van Eeden - International journal of molecular sciences, 2020 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is caused by the chronic exposure of the
lungs to toxic particles and gases. These exposures initiate a persistent innate and adaptive …

Pharmacologic Activities of Plant‐Derived Natural Products on Respiratory Diseases and Inflammations

D Timalsina, KP Pokhrel… - BioMed Research …, 2021 - Wiley Online Library
Respiratory inflammation is caused by an air‐mediated disease induced by polluted air,
smoke, bacteria, and viruses. The COVID‐19 pandemic is also a kind of respiratory disease …

Nanotechnology based advanced therapeutic strategies for targeting interleukins in chronic respiratory diseases

MS Hussain, P Sharma, DS Dhanjal, N Khurana… - Chemico-biological …, 2021 - Elsevier
Both communicable and non-communicable chronic respiratory conditions have accorded
for suffering of millions of people of all ages and stated to be leading cause of death …