Immobilization of pectinase on chitosan-alginate-clay composite beads: Experimental, DFT and molecular docking studies
A Aksu, S Çetinkaya, AF Yenidünya, ŞA Çetinus… - Journal of Molecular …, 2023 - Elsevier
Pectinase was immobilized on chitosan-alginate-clay (CAC) beads using epichlorohydrin
(ECH) as the crosslinker. Prepared beads and immobilization product were analyzed by …
(ECH) as the crosslinker. Prepared beads and immobilization product were analyzed by …
Isofraxidin: Antioxidant, Anti‐carbonic Anhydrase, Anti‐cholinesterase, Anti‐diabetic, and in Silico Properties
The development of innovative pharmacological formulations for the treatment and
prevention of various major diseases, including cancer, diabetes, and glaucoma, has been …
prevention of various major diseases, including cancer, diabetes, and glaucoma, has been …
Novel Quinazolinone Derivatives: Potential Synthetic Analogs for the Treatment of Glaucoma, Alzheimer's Disease and Diabetes Mellitus
Quinazolinones, which represent an important part of nitrogen‐containing six‐membered
heterocyclic compounds, are frequently used in drug design due to their wide biological …
heterocyclic compounds, are frequently used in drug design due to their wide biological …
Synthesis of new carboxylates and sulfonates containing thiazolidin-4-one ring and evaluation of inhibitory properties against some metabolic enzymes
A series of thizaolidin-4-one derivatives (3a-o) was synthesized with excellent yield (94–
97%) and the structures of the compounds were characterized with Fourier-transform …
97%) and the structures of the compounds were characterized with Fourier-transform …
Molecular hybrids integrated with imidazole and hydrazone structural motifs: Design, synthesis, biological evaluation, and molecular docking studies
In the present work, a series of compounds containing imidazole and hydrazone structural
frameworks were synthesized and characterized using various spectral techniques …
frameworks were synthesized and characterized using various spectral techniques …
Synthesis biological evaluation and molecular docking of isatin hybrids as anti-cancer and anti-microbial agents
Isatin, known as 1 H-indole-2, 3-dione, was originally recognised as a synthetic molecule
until its discovery in the fruits of the cannonball tree, Couroupita guianensis. It is naturally …
until its discovery in the fruits of the cannonball tree, Couroupita guianensis. It is naturally …
Crystal growth, morphological, mechanical, spectroscopic studies, optical properties, molecular docking, ADME/T, Hirshfeld surfaces analysis and theoretical …
Molecular organic–inorganic single crystals of 4-carboxyanilinium dihydrogenphosphate [4-
CADP] have been grown by the slow evaporation technique. The crystal structure was re …
CADP] have been grown by the slow evaporation technique. The crystal structure was re …
Synthesis, in vitro evaluation and molecular docking studies of novel thiophenyl thiazolyl-pyridine hybrids as potential anticancer agents
FO Ashmawy, SM Gomha, MA Abdallah, MEA Zaki… - Molecules, 2023 - mdpi.com
Many literature reports revealed the anticancer activity of pyridine and thiazole derivatives,
especially in lung cancer. Therefore, a new series of thiazolyl pyridines linked with …
especially in lung cancer. Therefore, a new series of thiazolyl pyridines linked with …
Synthesis, characterization, anti-tuberculosis activity and molecular modeling studies of thiourea derivatives bearing aminoguanidine moiety
The emergence of drug-resistant Mycobacterium tuberculosis strains has posed a driving
demand in the search for more effective treatment regimens for tuberculosis. In the present …
demand in the search for more effective treatment regimens for tuberculosis. In the present …
Synthesis, molecular modeling investigation, molecular dynamic and ADME prediction of some novel Mannich bases derived from 1, 2, 4-triazole, and assessment of …
S Manap, H Medetalibeyoğlu, A Kılıç… - Journal of …, 2023 - Taylor & Francis
A series of biologically active novel Mannich bases containing with a 1 H-1, 2, 4-triazole-5-
one ring were developed to evaluate the cytotoxic activity. For this purpose, the synthesized …
one ring were developed to evaluate the cytotoxic activity. For this purpose, the synthesized …