Objective: To revise the “Clinical Practice Guidelines for the Sustained Use of Sedatives and
Analgesics in the Critically Ill Adult” published in Critical Care Medicine in 2002. Methods …

These recommendations provide a data-supported approach. They are based on the
following:(1) formal review and analysis of the recently published world literature on the …

Importance Buprenorphine opioid agonist treatment (OAT) has established efficacy for
treating opioid dependency among persons seeking addiction treatment. However …

Test-based psychological assessment has been significantly affected by the health care
revolution in the United States during the past two decades. Despite new limitations on …

Objective.—To provide an evidence-based practice guideline on the pharmacological
management of alcohol withdrawal. Data Soureces.—English-language articles published …

This WHO collaborative project is the first phase of a programme of work aimed at
developing techniques for early identification and treatment of persons with hazardous and …

When The Natural History of Alcoholism was first published in 1983, it was acclaimed in the
press as the single most important contribution to the literature on alcoholism since the first …

Background Alcohol withdrawal delirium is the most serious manifestation of alcohol
withdrawal. Evidence suggests that appropriate care improves mortality, but systematic …

OBJECTIVE: To assess the effectiveness of brief interventions in heavy drinkers by
analyzing the outcome data and methodologic quality. DESIGN:(1) Qualitative analysis of …

The high prevalence of alcohol and drug abuse and mental illness imposes a substantial
financial burden on those affected and on society. The authors present estimates of the …