Physiology and pathophysiology of human airway mucus

DB Hill, B Button, M Rubinstein… - Physiological …, 2022 - journals.physiology.org
The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …

What are the respiratory effects of e-cigarettes?

JE Gotts, SE Jordt, R McConnell, R Tarran - bmj, 2019 - bmj.com
Electronic cigarettes (e-cigarettes) are alternative, non-combustible tobacco products that
generate an inhalable aerosol containing nicotine, flavors, propylene glycol, and vegetable …

Acute respiratory distress syndrome

MA Matthay, RL Zemans, GA Zimmerman… - Nature reviews Disease …, 2019 - nature.com
The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Chronic e-cigarette exposure alters the human bronchial epithelial proteome

A Ghosh, RC Coakley, T Mascenik… - American journal of …, 2018 - atsjournals.org
Rationale: E-cigarettes vaporize propylene glycol/vegetable glycerin (PG/VG), nicotine, and
flavorings. However, the long-term health effects of exposing lungs to vaped e-liquids are …

Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology

SU Chun-Yan, M Qian-Liang, K Rahman… - Chinese journal of …, 2015 - Elsevier
Salvia miltiorrhiza Bunge (SM) is a very popular medicinal plant that has been extensively
applied for many years to treat various diseases, especially coronary heart diseases and …

Aquaporin water channels–from atomic structure to clinical medicine

P Agre, LS King, M Yasui, WB Guggino… - The Journal of …, 2002 - Wiley Online Library
The water permeability of biological membranes has been a longstanding problem in
physiology, but the proteins responsible for this remained unknown until discovery of the …

The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin

CT Weaver, CO Elson, LA Fouser… - Annual Review of …, 2013 - annualreviews.org
The recent discovery of a new CD4+ T cell subset, Th17, has transformed our understanding
of the pathogenetic basis of an increasing number of chronic immune-mediated diseases …

From structure to disease: the evolving tale of aquaporin biology

LS King, D Kozono, P Agre - Nature reviews Molecular cell biology, 2004 - nature.com
Our understanding of the movement of water through cell membranes has been greatly
advanced by the discovery of a family of water-specific, membrane-channel proteins—the …

[HTML][HTML] Molecular mechanisms governing aquaporin relocalisation

A Markou, L Unger, M Abir-Awan, A Saadallah… - … et Biophysica Acta (BBA …, 2022 - Elsevier
The aquaporins (AQPs) form a family of integral membrane proteins that facilitate the
movement of water across biological membrane by osmosis, as well as facilitating the …

Human airway organoid engineering as a step toward lung regeneration and disease modeling

Q Tan, KM Choi, D Sicard, DJ Tschumperlin - Biomaterials, 2017 - Elsevier
Organoids represent both a potentially powerful tool for the study cell-cell interactions within
tissue-like environments, and a platform for tissue regenerative approaches. The …