Sialic acid receptors: the key to solving the enigma of zoonotic virus spillover

SV Kuchipudi, RK Nelli, A Gontu, R Satyakumar… - Viruses, 2021 - mdpi.com
Emerging viral diseases are a major threat to global health, and nearly two-thirds of
emerging human infectious diseases are zoonotic. Most of the human epidemics and …

A review of H5Nx avian influenza viruses

IA Nuñez, TM Ross - Therapeutic advances in vaccines and …, 2019 - journals.sagepub.com
Highly pathogenic avian influenza viruses (HPAIVs), originating from the
A/goose/Guangdong/1/1996 H5 subtype, naturally circulate in wild-bird populations …

Innate immune responses to avian influenza viruses in ducks and chickens

D Evseev, KE Magor - Veterinary sciences, 2019 - mdpi.com
Mallard ducks are important natural hosts of low pathogenic avian influenza (LPAI) viruses
and many strains circulate in this reservoir and cause little harm. Some strains can be …

The complex role of STAT3 in viral infections

SV Kuchipudi - Journal of immunology research, 2015 - Wiley Online Library
Signal transducer and activators of transcription‐3 (STAT3) regulates diverse biological
functions including cell growth, differentiation, and apoptosis. In addition, STAT3 plays a key …

Double-edged sword of JAK/STAT signaling pathway in viral infections: novel insights into virotherapy

M Mahjoor, G Mahmoudvand, S Farokhi… - Cell Communication and …, 2023 - Springer
The Janus kinase/signal transducer and activator of transcription (JAK/STAT) is an intricate
signaling cascade composed of various cytokines, interferons (IFN, growth factors, and other …

Resistant and susceptible chicken lines show distinctive responses to Newcastle disease virus infection in the lung transcriptome

MS Deist, RA Gallardo, DA Bunn, JCM Dekkers… - BMC genomics, 2017 - Springer
Background Newcastle disease virus (NDV) is a threat to poultry production worldwide. A
better understanding of mechanisms of resistance and susceptibility to this virus will improve …

Antagonizing cytokine-mediated JAK-STAT signaling by porcine reproductive and respiratory syndrome virus

L Yang, YJ Zhang - Veterinary microbiology, 2017 - Elsevier
Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling
pathway is activated by myriad cytokines, which are involved in regulation of cell growth …

Genes, inflammatory response, tolerance, and resistance to virus infections in migratory birds, bats, and rodents

PDC Pereira, DG Diniz, ER da Costa… - Frontiers in …, 2023 - frontiersin.org
Normally, the host immunological response to viral infection is coordinated to restore
homeostasis and protect the individual from possible tissue damage. The two major …

[HTML][HTML] Pathogenicity and tissue tropism of infectious bronchitis virus is associated with elevated apoptosis and innate immune responses

R Chhabra, SV Kuchipudi, J Chantrey, K Ganapathy - Virology, 2016 - Elsevier
To establish a characteristic host response to predict the pathogenicity and tissue tropism of
infectious bronchitis viruses (IBV), we investigated innate immune responses (IIR) and …

Determinants of knowledge and biosecurity preventive behaviors for highly pathogenic avian influenza risk among Chinese poultry farmers

B Cui, ZP Liu - Avian diseases, 2016 - meridian.allenpress.com
Biosecurity measures are the first line of defense against highly pathogenic avian influenza
(HPAI) on farms. It is generally recognized that an individual's behavior can be influenced by …