[HTML][HTML] MicroRNAs in Alzheimer's disease: Potential diagnostic markers and therapeutic targets

S Liu, M Fan, Q Zheng, S Hao, L Yang, Q Xia… - Biomedicine & …, 2022 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease, with cognitive
decline as the primary clinical feature. According to epidemiological statistics, 50 million …

Molecular and functional roles of microRNAs in the progression of hepatocellular carcinoma—a review

K Oura, A Morishita, T Masaki - International journal of molecular sciences, 2020 - mdpi.com
Liver cancer is the fourth leading cause of cancer deaths globally, of which hepatocellular
carcinoma (HCC) is the major subtype. Viral hepatitis B and C infections, alcohol abuse, and …

[HTML][HTML] Genetic and epigenetic factors determining NAFLD risk

W Jonas, A Schürmann - Molecular Metabolism, 2021 - Elsevier
Background Hepatic steatosis is a common chronic liver disease that can progress into more
severe stages of NAFLD or promote the development of life-threatening secondary diseases …

Alcohol-related liver disease: basic mechanisms and clinical perspectives

SY Liu, IT Tsai, YC Hsu - International journal of molecular sciences, 2021 - mdpi.com
Alcohol-related liver disease (ALD) refers to the liver damage occurring due to excessive
alcohol consumption and involves a broad spectrum of diseases that includes liver steatosis …

Alcohol-associated tissue injury: current views on pathophysiological mechanisms

L Simon, FM Souza-Smith… - Annual review of …, 2022 - annualreviews.org
At-risk alcohol use is a major contributor to the global health care burden and leads to
preventable deaths and diseases including alcohol addiction, alcoholic liver disease …

The impact of acute or chronic alcohol intake on the NF-κB signaling pathway in alcohol-related liver disease

AJ Nowak, B Relja - International Journal of Molecular Sciences, 2020 - mdpi.com
Ethanol misuse is frequently associated with a multitude of profound medical conditions,
contributing to health-, individual-and social-related damage. A particularly dangerous threat …

The role of exosomal miRNA in nonalcoholic fatty liver disease

A Mahmoudi, AE Butler… - Journal of cellular …, 2022 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) impacts more than one‐third of the population and
is linked with other metabolic diseases. The term encompasses a wide spectrum of …

[HTML][HTML] Molecular and cellular mediators of the gut-liver axis in the progression of liver diseases

A Bruneau, J Hundertmark, A Guillot, F Tacke - Frontiers in Medicine, 2021 - frontiersin.org
The gut-liver axis covers the bidirectional communication between the gut and the liver, and
thus includes signals from liver-to-gut (eg, bile acids, immunoglobulins) and from gut-to-liver …

Diagnosis and therapeutic management of liver fibrosis by MicroRNA

T Tadokoro, A Morishita, T Masaki - International Journal of Molecular …, 2021 - mdpi.com
Remarkable progress has been made in the treatment and control of hepatitis B and C viral
infections. However, fundamental treatments for diseases in which liver fibrosis is a key …

Fatty liver disease-alcoholic and non-alcoholic: similar but different

SDH Malnick, P Alin, M Somin… - International Journal of …, 2022 - mdpi.com
In alcohol-induced liver disease (ALD) and in non-alcoholic fatty liver disease (NAFLD),
there are abnormal accumulations of fat in the liver. This phenomenon may be related to …