Principles of molecular testing for hereditary cancer
C Mighton, JP Lerner‐Ellis - Genes, Chromosomes and Cancer, 2022 - Wiley Online Library
Molecular testing for hereditary cancers has rapidly advanced over the past two decades.
Next‐generation sequencing has been widely adopted, which has made molecular testing …
Next‐generation sequencing has been widely adopted, which has made molecular testing …
Racial disparity in the genomics of precision oncology of prostate cancer
T Le, PS Rojas, M Fakunle, FW Huang - Cancer Reports, 2023 - Wiley Online Library
Background Significant racial disparities in prostate cancer incidence and mortality have
been reported between African American Men (AAM), who are at increased risk for prostate …
been reported between African American Men (AAM), who are at increased risk for prostate …
[HTML][HTML] Clinical utility of polygenic risk scores: a critical 2023 appraisal
S Koch, J Schmidtke, M Krawczak… - Journal of Community …, 2023 - Springer
Since their first appearance in the context of schizophrenia and bipolar disorder in 2009,
polygenic risk scores (PRSs) have been described for a large number of common complex …
polygenic risk scores (PRSs) have been described for a large number of common complex …
Polygenic risk score in prostate cancer
JJ Oh, SK Hong - Current Opinion in Urology, 2022 - journals.lww.com
Emerging data from several studies regarding PRS in PCa could be the solution to adding
predictive value to PCa risk estimation. Although commercial markers are available …
predictive value to PCa risk estimation. Although commercial markers are available …
[HTML][HTML] Dose outside of the prostate is associated with improved outcomes for high-risk prostate cancer patients treated with brachytherapy boost
Background: One in three high-risk prostate cancer patients treated with radiotherapy recur.
Detection of lymph node metastasis and microscopic disease spread using conventional …
Detection of lymph node metastasis and microscopic disease spread using conventional …
Genome‑wide association study and polygenic risk scores predict psoriasis and its shared phenotypes in Taiwan
Psoriasis is a chronic inflammatory dermatological disease, and there is a lack of
understanding of the genetic factors involved in psoriasis in Taiwan. To establish …
understanding of the genetic factors involved in psoriasis in Taiwan. To establish …
How do experts in psychiatric genetics view the clinical utility of polygenic risk scores for schizophrenia?
Polygenic risk scores (PRS) are promising for identifying common variant‐related
inheritance for psychiatric conditions but their integration into clinical practice depends on …
inheritance for psychiatric conditions but their integration into clinical practice depends on …
[图书][B] Exploring and Exploiting Genetic Risk for Psychiatric Disorders
An edited volume that looks at the state of psychiatric genetics and how to chart a path
forward. In this edited collection, experts from psychiatric and statistical genetics …
forward. In this edited collection, experts from psychiatric and statistical genetics …
[HTML][HTML] The Combined Effect of Polygenic Risk Score and Prostate Health Index in Chinese Men Undergoing Prostate Biopsy
To date, the combined effect of polygenic risk score (PRS) and prostate health index (phi) on
PCa diagnosis in men undergoing prostate biopsy has never been investigated. A total of …
PCa diagnosis in men undergoing prostate biopsy has never been investigated. A total of …
Racial Disparity in Utilizing Genetic Testing for Personalized Care of Prostate Cancer
T Le, PS Rojas, M Fakunle, F Huang - Authorea Preprints, 2023 - techrxiv.org
Significant racial disparities in prostate cancer incidence and mortality have been reported
between African American Men (AAM) who are at increased risk for prostate cancer, and …
between African American Men (AAM) who are at increased risk for prostate cancer, and …