Analyzing the Virchow pioneering report on brain corpora amylacea: shedding light on recurrent controversies
M Riba, C Romera, R Alsina, G Alsina-Scheer… - Brain Structure and …, 2023 - Springer
The first report of corpora amylacea (CA) is attributed to Morgagni, who described them in
the prostate in the eighteenth century. Nearly a hundred years later, and following the lead …
the prostate in the eighteenth century. Nearly a hundred years later, and following the lead …
ApoE4 expression disrupts tau uptake, trafficking, and clearance in astrocytes
M Eisenbaum, A Pearson, C Ortiz, M Mullan… - Glia, 2024 - Wiley Online Library
Tauopathies are a collection of neurodegenerative diseases characterized by the
accumulation of pathogenic aggregates of the microtubule‐associated protein tau. Despite …
accumulation of pathogenic aggregates of the microtubule‐associated protein tau. Despite …
Wasteosomes (corpora amylacea) as a hallmark of chronic glymphatic insufficiency
M Riba, J Del Valle, L Molina-Porcel… - Proceedings of the …, 2022 - National Acad Sciences
In different organs and tissues, the lymphatic system serves as a drainage system for
interstitial fluid and is useful for removing substances that would otherwise accumulate in the …
interstitial fluid and is useful for removing substances that would otherwise accumulate in the …
Uncovering tau in wasteosomes (corpora amylacea) of Alzheimer's disease patients
M Riba, J Del Valle, C Romera, R Alsina… - Frontiers in Aging …, 2023 - frontiersin.org
Brain corpora amylacea, recently renamed as wasteosomes, are polyglucosan bodies that
appear during aging and some neurodegenerative conditions. They collect waste …
appear during aging and some neurodegenerative conditions. They collect waste …
Distribution of corpora amylacea in the human midbrain: using synchrotron radiation phase-contrast microtomography, high-field magnetic resonance imaging, and …
Corpora amylacea (CA) are polyglucosan aggregated granules that accumulate in the
human body throughout aging. In the cerebrum, CA have been found in proximity to …
human body throughout aging. In the cerebrum, CA have been found in proximity to …
Corpora amylacea negatively correlate with hippocampal tau pathology in Alzheimer's disease
JD Dallmeier, R Gober, RT Vontell, A Barreda… - Frontiers in …, 2024 - frontiersin.org
Introduction Severity and distribution of aggregated tau and neurofibrillary tangles (NFT) are
strongly correlated with the clinical presentation of Alzheimer's disease (AD). Clearance of …
strongly correlated with the clinical presentation of Alzheimer's disease (AD). Clearance of …
Astrocytes are involved in the formation of corpora amylacea-like structures from neuronal debris in the CA1 region of the rat hippocampus after ischemia
Recently, we demonstrated that the corpora amylacea (CA), a glycoprotein-rich aggregate
frequently found in aged brains, accumulates in the ischemic hippocampus and that …
frequently found in aged brains, accumulates in the ischemic hippocampus and that …
Contribution of astrocytes to the neurovascular elimination of tau
M Eisenbaum, C Bachmeier - Neural Regeneration Research, 2024 - journals.lww.com
Tauopathies encompass a collection of chronic, progressive neurodegenerative diseases,
including Alzheimer's disease (AD), chronic traumatic encephalopathy, and corticobasal …
including Alzheimer's disease (AD), chronic traumatic encephalopathy, and corticobasal …
Polyglucosan body disease in an aged chimpanzee (Pan troglodytes)
S Gumber, F Connor‐Stroud, D Howard… - …, 2023 - Wiley Online Library
A 57‐year‐old female chimpanzee presented with a brief history of increasing lethargy and
rapidly progressive lower‐limb weakness that culminated in loss of use. Postmortem …
rapidly progressive lower‐limb weakness that culminated in loss of use. Postmortem …
星形胶质细胞在神经血管消除tau 中的作用
M Eisenbaum, C Bachmeier - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
Tauopathies encompass a collection of chronic, progressive neurodegenerative diseases,
including Alzheimer's disease (AD), chronic traumatic encephalopathy, and corticobasal …
including Alzheimer's disease (AD), chronic traumatic encephalopathy, and corticobasal …