Mutation burden, hypoxia, and immunoediting contribute to altered metabolic profiles in
tumor cells, resulting in a tumor microenvironment (TME) characterized by accumulation of …

Neutrophils are the most abundant white blood cells in the circulation and act as the first line
of defense against infections. Increasing evidence suggests that neutrophils possess …

Breast cancer, a highly fatal disease due to its tendency to metastasize, is the most prevalent
form of malignant tumors among women worldwide. Numerous studies indicate that breast …

Over the past decade, research has prominently established neutrophils as key contributors
to the intricate landscape of tumor immune biology. As polymorphonuclear granulocytes …

Precise molecular characterization of circulating polymorphonuclear myeloid-derived
suppressor cells (PMN-MDSCs) is hampered by their mixed composition of mature and …

The notion that neutrophils only perform a specific set of single functions in the body has
changed with the advancement of research methods. As the most abundant myeloid cells in …

Characterizing the relative onset time, strength, and duration of molecular signals is critical
for understanding the operation of signal transduction and genetic regulatory networks …

Transplantation is a life-saving therapy for patients with end-stage organ disease.
Successful outcomes after transplantation require mitigation of the post-transplant …

Emerging evidence suggests that local tumor radiotherapy reshapes the repertoire of
circulating myeloid-derived suppressor cells (MDSCs) and leads to their infiltration into the …

Objective: Neutrophils are one of the most predominant infiltrating leukocytes in lung cancer
tissues and are associated with lung cancer progression. How neutrophils promote lung …