[HTML][HTML] Nanocarriers based on bacterial membrane materials for cancer vaccine delivery
Here we present a protocol for the construction and use of two types of nanocarrier based on
bacterial membrane materials for cancer vaccine delivery. Cancer vaccines induce tumor …
bacterial membrane materials for cancer vaccine delivery. Cancer vaccines induce tumor …
Polymeric long-acting drug delivery systems (LADDS) for treatment of chronic diseases: Inserts, patches, wafers, and implants
Non-oral long-acting drug delivery systems (LADDS) encompass a range of technologies for
precisely delivering drug molecules into target tissues either through the systemic circulation …
precisely delivering drug molecules into target tissues either through the systemic circulation …
Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines
Cancer vaccines based on resected tumors from patients have gained great interest as an
individualized cancer treatment strategy. However, eliciting a robust therapeutic effect with …
individualized cancer treatment strategy. However, eliciting a robust therapeutic effect with …
Trial watch: Dendritic cell (DC)-based immunotherapy for cancer
Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable
development over recent decades. However, this field is currently in a state of flux toward …
development over recent decades. However, this field is currently in a state of flux toward …
[HTML][HTML] Exosomes: promising delivery tools for overcoming blood-brain barrier and glioblastoma therapy
Gliomas make up virtually 80% of all lethal primary brain tumors and are categorized based
on their cell of origin. Glioblastoma is an astrocytic tumor that has an inferior prognosis …
on their cell of origin. Glioblastoma is an astrocytic tumor that has an inferior prognosis …
A phase I study of autologous dendritic cell vaccine pulsed with allogeneic stem-like cell line lysate in patients with newly diagnosed or recurrent glioblastoma
JL Hu, OA Omofoye, JD Rudnick, S Kim… - Clinical Cancer …, 2022 - AACR
Purpose: Glioblastoma (GBM) is a heterogeneous malignancy with multiple subpopulations
of cancer cells present within any tumor. We present the results of a phase I clinical trial …
of cancer cells present within any tumor. We present the results of a phase I clinical trial …
[HTML][HTML] Immune escape in glioblastoma multiforme and the adaptation of immunotherapies for treatment
JRD Pearson, S Cuzzubbo, S McArthur… - Frontiers in …, 2020 - frontiersin.org
Glioblastoma multiforme (GBM) is the most frequently occurring primary brain tumor and has
a very poor prognosis, with only around 5% of patients surviving for a period of 5 years or …
a very poor prognosis, with only around 5% of patients surviving for a period of 5 years or …
[HTML][HTML] Personalised therapeutic approaches to glioblastoma: A systematic review
OD Mowforth, J Brannigan, M El Khoury… - Frontiers in …, 2023 - frontiersin.org
Introduction Glioblastoma is the most common and malignant primary brain tumour with
median survival of 14.6 months. Personalised medicine aims to improve survival by …
median survival of 14.6 months. Personalised medicine aims to improve survival by …
[HTML][HTML] Randomized controlled immunotherapy clinical trials for GBM challenged
SW Van Gool, J Makalowski, S Fiore, T Sprenger… - Cancers, 2020 - mdpi.com
Simple Summary Although multiple meta-analyses on active specific immunotherapy
treatment for glioblastoma multiforme (GBM) have demonstrated a significant prolongation of …
treatment for glioblastoma multiforme (GBM) have demonstrated a significant prolongation of …
[HTML][HTML] Immunotherapy for recurrent glioblastoma: practical insights and challenging prospects
X Wang, J Lu, G Guo, J Yu - Cell Death & Disease, 2021 - nature.com
Glioblastoma (GB) is the most common high-grade intracranial malignant tumor with highly
malignant biological behavior and a high recurrence rate. Although anti-PD-1/PD-L1 …
malignant biological behavior and a high recurrence rate. Although anti-PD-1/PD-L1 …