Autophagy is a conserved lysosomal pathway for the degradation of cytoplasmic
components. Basal autophagy in kidney cells is essential for the maintenance of kidney …

Nanotechnology is a growing field, with many potential biomedical applications of
nanomedicine for the treatment of different diseases, particularly cancer, on the horizon …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a vital transcription factor and its induction
is of significant importance for protecting against oxidative damage. Increased levels of …

Background Autosomal dominant polycystic kidney disease (ADPKD), the most common
inherited kidney disease, is regulated by different forms of cell death, including apoptosis …

Our study explored the tumor-suppressive effect of curcumin on cervical cancer cells.
Cervical cancer is one of the most common cancers among women worldwide. Acquired …

Abstract Arsenic (As) and copper (Cu) are two common contaminants in the environment.
When organisms are exposed to As or/and Cu in large quantities or for sustained periods …

Despite the recent launch of tolvaptan, the search for safer polycystic kidney disease (PKD)
drugs continues. Ciclopirox (CPX) or its olamine salt (CPX-O) is contained in a number of …

Mutations in the gene encoding polycystin-1 (PC1) are the most common cause of
autosomal dominant polycystic kidney disease (ADPKD). Cysts in ADPKD exhibit a Warburg …

Copper (Cu), an environmental heavy metal pollutant, has been widely researched in its
toxicology. Recently, an increasing number of mitochondrial microRNAs (mitomiRs) have …

Copper (Cu) is one of the ubiquitous environmental pollutants which have raised wide
concerns about the potential toxic effects and public health threat. For deeply investigating …