Introduction: Periodontitis is a non-communicable chronic inflammatory disease with a
systemic burden. Animal models of induced periodontitis help elucidate the mechanisms by …

Plasma membrane-associated Toll-like receptor (TLR2 and TLR4) signaling contributes to
oral microbe infection-induced periodontitis and atherosclerosis. We recently reported that …

Low bilirubin kernicterus in preterm neonates, though rare, remains an unpredictable and
refractory form of brain injury. Hypoalbuminemia, co-morbid CNS insult (s), infection, and …

ABSTRACT Toll-like receptor 9 (TLR9)-deficient (TLR9−/−) mice are resistant to
periodontitis, a disease characterized by a dysbiotic microbiota and deregulated immune …

Introduction: prelabor rupture of membranes (PROM) is a major factor that affects pregnancy
outcome. Results from previous studies have suggested that there is an association …

Objectives Physiological changes and shifts in the oral microbiota composition during
pregnancy may affect the maternal immune system. Uncomplicated pregnancy is associated …

Objective A growing body of research has investigated the human microbiota and
pregnancy outcomes, especially preterm birth. Most studies of the prenatal microbiota have …

Preterm premature rupture of membranes (pPROM) poses a significant threat to fetal viability
and increases the risk for newborn morbidities. The perinatal period of preterm infants …

Maternal environmental enteric dysfunction (EED) encompasses undernutrition with an
inflammatory gut profile, a variable degree of dysbiosis and increased translocation of …

BACKGROUND: Physiological changes that occur during pregnancy involve, as a natural
consequence, also modifications of oral microbiome. However, the addition with microbial …