[HTML][HTML] Small extracellular vesicles in cancer

K Abhange, A Makler, Y Wen, N Ramnauth, W Mao… - Bioactive Materials, 2021 - Elsevier
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

Enhanced permeability and retention effect: A key facilitator for solid tumor targeting by nanoparticles

VR Shinde, N Revi, S Murugappan, SP Singh… - Photodiagnosis and …, 2022 - Elsevier
Exploring the enhanced permeability and retention (EPR) effect through therapeutic
nanoparticles has been a subject of considerable interest in tumor biology. This passive …

[HTML][HTML] Novel drugs with high efficacy against tumor angiogenesis

S Qi, S Deng, Z Lian, K Yu - International Journal of Molecular Sciences, 2022 - mdpi.com
Angiogenesis is involved in physiological and pathological processes in the body. Tumor
angiogenesis is a key factor associated with tumor growth, progression, and metastasis …

[HTML][HTML] A systematic review of miR-29 in cancer

JJ Kwon, TD Factora, S Dey, J Kota - Molecular Therapy-Oncolytics, 2019 - cell.com
MicroRNAs (miRNA) are small non-coding RNAs (∼ 22 nt in length) that are known as
potent master regulators of eukaryotic gene expression. miRNAs have been shown to play a …

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

J Galon, D Bruni - Nature reviews Drug discovery, 2019 - nature.com
Immunotherapies are the most rapidly growing drug class and have a major impact in
oncology and on human health. It is increasingly clear that the effectiveness of …

Insights on the potential oncogenic impact of long non-coding RNA nicotinamide nucleotide transhydrogenase antisense RNA 1 in different cancer types; integrating …

NM El-Sheikh, AI Abulsoud, EF Wasfey… - Pathology-Research and …, 2022 - Elsevier
Long non-coding RNAs (lncRNAs) are becoming more prevalent in the cancer field arena,
with functional roles in both oncogenic and onco-suppressive pathways. Despite their …

[HTML][HTML] The plasminogen–activator plasmin system in physiological and pathophysiological angiogenesis

AA Ismail, BT Shaker, K Bajou - International Journal of Molecular …, 2021 - mdpi.com
Angiogenesis is a process associated with the migration and proliferation of endothelial
cells (EC) to form new blood vessels. It is involved in various physiological and …

Angiopoietin inhibitors: A review on targeting tumor angiogenesis

D Parmar, M Apte - European journal of pharmacology, 2021 - Elsevier
Angiogenesis is the process of formation of new blood vessels from existing ones. Vessels
serve the purpose of providing oxygen, nutrients and removal of waste from the cells. The …

[HTML][HTML] Cytokines and chemokines as mediators of prostate cancer metastasis

TO Adekoya, RM Richardson - International journal of molecular sciences, 2020 - mdpi.com
The consequences of prostate cancer metastasis remain severe, with huge impact on the
mortality and overall quality of life of affected patients. Despite the convoluted interplay and …

Chalcones: Promising therapeutic agents targeting key players and signaling pathways regulating the hallmarks of cancer

AA WalyEldeen, S Sabet, HM El-Shorbagy… - Chemico-Biological …, 2023 - Elsevier
The need for innovative anticancer treatments with high effectiveness and low toxicity is
urgent due to the development of malignancies that are resistant to chemotherapeutic …