Acute kidney injury

C Ronco, R Bellomo, JA Kellum - The Lancet, 2019 - thelancet.com
Acute kidney injury (AKI) is defined by a rapid increase in serum creatinine, decrease in
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …

Immunopathophysiology of trauma-related acute kidney injury

DAC Messerer, R Halbgebauer, B Nilsson… - Nature Reviews …, 2021 - nature.com
Physical trauma can affect any individual and is globally accountable for more than one in
every ten deaths. Although direct severe kidney trauma is relatively infrequent, extrarenal …

Intra-abdominal hypertension and abdominal compartment syndrome in critically ill patients: A narrative review of past, present, and future steps

M Smit, M van Meurs, JG Zijlstra - Scandinavian Journal of …, 2022 - journals.sagepub.com
Background and objective: Intra-abdominal hypertension is frequently present in critically ill
patients and is an independent predictor for mortality. In this narrative review, we aim to …

A combination of SOFA score and biomarkers gives a better prediction of septic AKI and in-hospital mortality in critically ill surgical patients: a pilot study

CW Lee, H Kou, HS Chou, H Chou, SF Huang… - World Journal of …, 2018 - Springer
Background Sepsis is a syndrome characterized by a constellation of clinical manifestations
and a significantly high mortality rate in the surgical intensive care unit (ICU). It is frequently …

Intra-abdominal hypertension in cardiac surgery patients: a multicenter observational sub-study of the Accuryn registry

AK Khanna, S Minear, A Kurz, V Moll, K Stanton… - Journal of Clinical …, 2023 - Springer
Intra-abdominal hypertension (IAH) is frequently present in the critically ill and is associated
with increased morbidity and mortality. Conventionally, intermittent 'spot-check'manual …

Reinterpreting renal hemodynamics: the importance of venous congestion and effective organ perfusion in acute kidney injury

C Kopitko, T Gondos, T Fülöp, L Medve - The American journal of the …, 2020 - Elsevier
The significance of effective renal perfusion is relatively underemphasized in the current
literature. From a renal standpoint, besides optimizing cardiac output, renal perfusion should …

Management of chronic kidney disease patients in the intensive care unit: mixing acute and chronic illness

S De Rosa, S Samoni, G Villa, C Ronco - Blood purification, 2017 - karger.com
Patients with chronic kidney disease (CKD) are at high risk for developing critical illness and
for admission to intensive care units (ICU).'Critically ill CKD patients' frequently develop an …

Intra-parenchymal renal resistive index variation (IRRIV) describes renal functional reserve (RFR): pilot study in healthy volunteers

S Samoni, F Nalesso, M Meola, G Villa… - Frontiers in …, 2016 - frontiersin.org
An increase of glomerular filtration rate after protein load represents renal functional reserve
(RFR) and is due to afferent arteriolar vasodilation. Lack of RFR may be a risk factor for …

Perioperative renoprotection: general mechanisms and treatment approaches

L Molinari, A Sakhuja, JA Kellum - Anesthesia & Analgesia, 2020 - journals.lww.com
In the perioperative setting, acute kidney injury (AKI) is a frequent complication, and AKI
itself is associated with adverse outcomes such as higher risk of chronic kidney disease and …

Mediators of regional kidney perfusion during surgical pneumo-peritoneum creation and the risk of acute kidney injury—a review of basic physiology

C Kopitkó, L Medve, T Gondos, KMM Soliman… - Journal of Clinical …, 2022 - mdpi.com
Acute kidney injury (AKI), especially if recurring, represents a risk factor for future chronic
kidney disease. In intensive care units, increased intra-abdominal pressure is well …