The promise of organ and tissue preservation to transform medicine

S Giwa, JK Lewis, L Alvarez, R Langer, AE Roth… - Nature …, 2017 - nature.com
The ability to replace organs and tissues on demand could save or improve millions of lives
each year globally and create public health benefits on par with curing cancer. Unmet needs …

Dimethyl sulfoxide: a central player since the dawn of cryobiology, is efficacy balanced by toxicity?

M Awan, I Buriak, R Fleck, B Fuller, A Goltsev… - Regenerative …, 2020 - Future Medicine
Dimethyl sulfoxide (DMSO) is the cryoprotectant of choice for most animal cell systems since
the early history of cryopreservation. It has been used for decades in many thousands of cell …

The roles of reactive oxygen species and antioxidants in cryopreservation

JS Len, WSD Koh, SX Tan - Bioscience reports, 2019 - portlandpress.com
Cryopreservation has facilitated advancement of biological research by allowing the storage
of cells over prolonged periods of time. While cryopreservation at extremely low …

The need for novel cryoprotectants and cryopreservation protocols: Insights into the importance of biophysical investigation and cell permeability

R Raju, SJ Bryant, BL Wilkinson, G Bryant - Biochimica et Biophysica Acta …, 2021 - Elsevier
Background Cryopreservation is a key method of preservation of biological material for both
medical treatments and conservation of endangered species. In order to avoid cellular …

Advanced biomaterials in cell preservation: Hypothermic preservation and cryopreservation

Y Ma, L Gao, Y Tian, P Chen, J Yang, L Zhang - Acta Biomaterialia, 2021 - Elsevier
Cell-based medicine has made great advances in clinical diagnosis and therapy for various
refractory diseases, inducing a growing demand for cell preservation as support technology …

Cryopreservation of hematopoietic stem cells: emerging assays, cryoprotectant agents, and technology to improve outcomes

K Hornberger, G Yu, D McKenna, A Hubel - Transfusion Medicine and …, 2019 - karger.com
Hematopoietic stem cell (HSC) therapy is widely used to treat a growing number of
hematological and non-hematological diseases. Cryopreservation of HSCs allows for cells …

Cryopreservation: a comprehensive overview, challenges, and future perspectives

A Parihar, A Kumar, U Panda, R Khan… - Advanced …, 2023 - Wiley Online Library
Cryopreservation is the most prevalent method of long‐term cell preservation. Effective cell
cryopreservation depends on freezing, adequate storage, and correct thawing techniques …

[HTML][HTML] Effects of storage media, supplements and cryopreservation methods on quality of stem cells

OD Erol, B Pervin, ME Seker… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
Despite a vast amount of different methods, protocols and cryoprotective agents (CPA), stem
cells are often frozen using standard protocols that have been optimized for use with cell …

Principles and protocols for post-cryopreservation quality evaluation of stem cells in novel biomedicine

J Xie, MD Ekpo, J Xiao, H Zhao, X Bai… - Frontiers in …, 2022 - frontiersin.org
Stem cell therapy is a thriving topic of interest among researchers and clinicians due to
evidence of its effectiveness and promising therapeutic advantage in numerous disease …

Ice recrystallization inhibiting polymers enable glycerol-free cryopreservation of microorganisms

M Hasan, AER Fayter, MI Gibson - Biomacromolecules, 2018 - ACS Publications
All modern molecular biology and microbiology is underpinned by not only the tools to
handle and manipulate microorganisms but also those to store, bank, and transport them …