Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …

Maintenance of endothelial cell integrity is an important component of human health and
disease since the endothelium can perform various functions including regulation of …

Antiplatelet therapy is key to reducing local thrombotic complications and systemic
ischaemic events among patients undergoing percutaneous coronary interventions (PCI) …

Aortic aneurysm is a vascular disease whereby the ECM (extracellular matrix) of a blood
vessel degenerates, leading to dilation and eventually vessel wall rupture. Recently, it was …

Hemostasis encompasses a set of tightly regulated processes that govern blood clotting,
platelet activation, and vascular repair. Upon vascular injury, the hemostatic system initiates …

Over the last 40 years, our understanding of the pathogenesis of myocardial infarction has
evolved and allowed new treatment strategies that have greatly improved survival. Over the …

Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better
understanding of the mechanisms underlying CVD is key for better management or …

Cardiovascular diseases (CVDs) constitute the prime cause of global mortality, with an
immense impact on patient quality of life and disability. Clinical evidence has revealed a …

Complex interactions exist between cytokines and the interleukin family plays a fundamental
role in inflammation. Particularly circulating IL-1β, IL-6 and IL-8 are unregulated in systemic …

A Tale of Coronary Artery Disease and Myocardial Infarction | NEJM Skip to main content NEJM
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