Cancer is a condition characterized by remarkably enhanced rates of cell proliferation
paired with evasion of cell death. These deregulated cellular processes take place following …

Prostate cancer is one of the life threatening disorders of male. Although, over the last two
decades, a high rate of overdiagnosis, and overtreatment has lowered the incidence rate of …

Galectins, a family of glycan-binding proteins, influence tumor progression by modulating
interactions between tumor, endothelial, stromal, and immune cells. Despite considerable …

The majority of prostate cancer (PCa) cases are diagnosed as a localized disease. Definitive
treatment, active surveillance or watchful waiting are employed as therapeutic paradigms …

Background: Aberrant mitogen/extracellular signal-regulated kinase 5 (MEK5)–extracellular
signal-regulated protein kinase 5 (ERK5)-mediated signalling has been implicated in a …

Abstract Background The leaves of Strobilanthes crispus (S. crispus) which is native to the
regions of Madagascar to the Malay Archipelago, are used in folk medicine for their …

Prostate cancer (PCa) is the second leading cause of cancer-associated death in men. Once
a tumor is established it may attain further characteristics via mutations or hypoxia, which …

Simple Summary Prostate specific membrane antigen and galectins are proteins expressed
on cell surface and their expression is associated with cancer growth and spread. The goal …

Cisplatin is one of the most potent chemotherapeutic agents for the treatment of many types
of solid tumours. Nevertheless, it is not the first‐line drug for prostate cancer chemotherapy …

Rel/NF-ΚB transcription factors are key regulators of genes implicated in inflammatory and
immune activation, cell growth and protection from apoptosis. Constitutive activation of NF …