Metabolic Syndrome and Atrial Fibrillation: Different Entities or Combined Disorders

GE Zakynthinos, V Tsolaki, E Oikonomou… - Journal of Personalized …, 2023 - mdpi.com
Obesity, hypertension, insulin resistance, and dyslipidemia are all clusters of an entity called
“Metabolic Syndrome”. The global trends of this syndrome's incidence/prevalence continue …

Direct oral anticoagulants: an overview of indications, pharmacokinetics, comorbidities, and perioperative management

E Moras, K Gandhi, M Khan, A Moras, J Choi… - Cardiology in …, 2023 - journals.lww.com
Direct oral anticoagulants (DOACs) have catalyzed a significant paradigm shift in the
landscape of anticoagulant therapy, emerging as pivotal agents for the prevention of stroke …

Prediction of early neurological deterioration in acute ischemic stroke patients treated with intravenous thrombolysis

T Tian, L Wang, J Xu, Y Jia, K Xue… - Journal of Cerebral …, 2023 - journals.sagepub.com
A proportion of acute ischemic stroke (AIS) patients suffer from early neurological
deterioration (END) within 24 hours following intravenous thrombolysis (IVT), which greatly …

Real life results of direct-acting oral anticoagulants recommended-dose in obese vs normal-weight patients with venous thromboembolism

JA Rueda-Camino, R Barba, S Otálora… - Thrombosis …, 2024 - Elsevier
Background There is scarce evidence on the effectiveness and safety of recommended-
dose direct acting oral anticoagulants (DOACs) in obese patients with venous …

An update on applications and limitations of direct oral anticoagulants

S Wei, A Sawhney, H Khandait, A Meda… - The Egyptian Journal of …, 2023 - Springer
A major advancement in the field of medicine has been the introduction and usage of direct
oral anticoagulants (DOACs) such as dabigatran (Pradaxa), apixaban (Eliquis), and …

Safety and efficacy of direct oral anticoagulants in comparison to warfarin in obese patients with atrial fibrillation: A systematic review and meta‐analysis

A Adelkhanova, PR Oli, DB Shrestha… - Health Science …, 2024 - Wiley Online Library
Abstract Background and Aim Obesity affects nearly 650 million adults worldwide, and the
prevalence is steadily rising. This condition has significant adverse effects on cardiovascular …

The Importance of Assessing Drug Pharmacokinetics and Pharmacodynamics in the Obese Population During Drug Development

KT Moore, PN Zannikos, JC Masters… - The Journal of …, 2023 - Wiley Online Library
Obesity remains a US national health crisis and a growing concern worldwide.
Concerningly, individuals who are obese are at an increased risk for comorbid diseases that …

Safety and efficacy of oral anticoagulants in extreme weights

J Chin-Hon, L Davenport, J Huang, M Akerman… - Thrombosis …, 2023 - Elsevier
Abstract Background The 2021 International Society on Thrombosis and
Haemostasis'(ISTH) recommends standard doses of apixaban and rivaroxaban regardless …

[PDF][PDF] Potenciální využití laboratorního monitorování při individualizaci dávkování přímých perorálních antikoagulancií-přehled literatury

K Zyková, A Rejman Patková, M Penka… - Vnitřní …, 2023 - casopisvnitrnilekarstvi.cz
Methods: Publications from Pubmed and Scopus databases assessing the effect of
advanced age, altered renal function, sarcopenia, obesity, medication adherence, and drug …