Genetic and epigenetic regulation of abdominal aortic aneurysms
KD Mangum, MA Farber - Clinical genetics, 2020 - Wiley Online Library
Abdominal aortic aneurysms (AAAs) are focal dilations of the aorta that develop from
degenerative changes in the media and adventitia of the vessel. Ruptured AAAs have a …
degenerative changes in the media and adventitia of the vessel. Ruptured AAAs have a …
Abdominal aortic aneurysms and diabetes mellitus
K Pafili, I Gouni-Berthold, N Papanas… - Journal of Diabetes and …, 2015 - Elsevier
There is accumulating evidence that risk profiles differ between coronary artery disease and
abdominal aortic aneurysms (AAAs). However, diabetes mellitus (DM) appears to be …
abdominal aortic aneurysms (AAAs). However, diabetes mellitus (DM) appears to be …
Meta-analysis of abdominal aortic aneurysm in patients with coronary artery disease
A Elkalioubie, S Haulon, A Duhamel, M Rosa… - The American Journal of …, 2015 - Elsevier
The high coronary artery disease (CAD) prevalence in patients with abdominal aortic
aneurysm (AAA) is well known. However, the inverse relation has been little explored. We …
aneurysm (AAA) is well known. However, the inverse relation has been little explored. We …
Simvastatin attenuates abdominal aortic aneurysm formation favoured by lack of Nrf2 transcriptional activity
A Kopacz, E Werner… - Oxidative medicine …, 2020 - Wiley Online Library
Surgical intervention is currently the only option for an abdominal aortic aneurysm (AAA),
preventing its rupture and sudden death of a patient. Therefore, it is crucial to determine the …
preventing its rupture and sudden death of a patient. Therefore, it is crucial to determine the …
ADAM (a disintegrin and metalloproteinase) 15 deficiency exacerbates Ang II (angiotensin II)–Induced aortic remodeling leading to abdominal aortic aneurysm
S Jana, M Chute, M Hu, G Winkelaar… - … and Vascular Biology, 2020 - Am Heart Assoc
Objective: ADAM (a disintegrin and metalloproteinase) 15—a membrane-bound
metalloprotease from the ADAM (disintegrin and metalloproteinase) family—has been linked …
metalloprotease from the ADAM (disintegrin and metalloproteinase) family—has been linked …
[HTML][HTML] Potential influencing factors of aortic diameter at specific segments in population with cardiovascular risk
T Chen, X Yang, X Fang, L Tang, Y Zhang… - BMC Cardiovascular …, 2022 - Springer
Background Aortic diameter is a critical parameter for the diagnosis of aortic dilated
diseases. Aortic dilation has some common risk factors with cardiovascular diseases. This …
diseases. Aortic dilation has some common risk factors with cardiovascular diseases. This …
[HTML][HTML] Myostatin mediates abdominal aortic atherosclerosis progression by inducing vascular smooth muscle cell dysfunction and monocyte recruitment
D Verzola, S Milanesi, M Bertolotto, S Garibaldi… - Scientific reports, 2017 - nature.com
Myostatin (Mstn) is a skeletal muscle growth inhibitor involved in metabolic disorders and
heart fibrosis. In this study we sought to verify whether Mstn is also operative in …
heart fibrosis. In this study we sought to verify whether Mstn is also operative in …
[图书][B] Atherosclerosis pathogenesis and microvascular dysfunction
A Haverich, EC Boyle - 2019 - Springer
Based on surgical observations, I've remained critical about many of the hypotheses
regarding the pathogenesis of atherosclerosis, since two important paradigms appear to be …
regarding the pathogenesis of atherosclerosis, since two important paradigms appear to be …
[HTML][HTML] SOX4 is a novel phenotypic regulator of endothelial cells in atherosclerosis revealed by single-cell analysis
Introduction Atherosclerotic complications represent the leading cause of cardiovascular
mortality globally. Dysfunction of endothelial cells (ECs) often initiates the pathological …
mortality globally. Dysfunction of endothelial cells (ECs) often initiates the pathological …
Molecular pathogenesis of genetic and sporadic aortic aneurysms and dissections
YH Shen, SA LeMaire - Current problems in surgery, 2017 - Elsevier
The aorta is the largest artery and can be divided into several segments (Fig 1). The
diaphragm divides the aorta into the thoracic and abdominal aorta. The thoracic aorta …
diaphragm divides the aorta into the thoracic and abdominal aorta. The thoracic aorta …