Role of the microbiome in human development

MG Dominguez-Bello, F Godoy-Vitorino, R Knight… - Gut, 2019 - gut.bmj.com
The host-microbiome supraorganism appears to have coevolved and the unperturbed
microbial component of the dyad renders host health sustainable. This coevolution has likely …

Gestational diabetes mellitus: a harbinger of the vicious cycle of diabetes

EU Alejandro, TP Mamerto, G Chung… - International journal of …, 2020 - mdpi.com
Gestational diabetes mellitus (GDM), characterized by a transitory form of diabetes induced
by insulin resistance and pancreatic β-cell dysfunction during pregnancy, has been …

Liquid biopsies: applications for cancer diagnosis and monitoring

I Martins, IP Ribeiro, J Jorge, AC Gonçalves… - Genes, 2021 - mdpi.com
The minimally—or non-invasive detection of circulating tumor-derived components in
biofluids, such as blood, liquid biopsy is a revolutionary approach with significant potential …

[HTML][HTML] Intrauterine growth restriction: Clinical consequences on health and disease at adulthood

JB Armengaud, C Yzydorczyk, B Siddeek… - Reproductive …, 2021 - Elsevier
Intrauterine growth restriction (IUGR) affects 10–15% of all pregnancies worldwide. IUGR
may result from maternal, placental or fetal origin. Maternal malnutrition before and during …

Cadmium: Toxic effects on placental and embryonic development

HX Geng, L Wang - Environmental toxicology and pharmacology, 2019 - Elsevier
Cadmium is a non-essential trace metal that has strong teratogenic and mutagenic effects in
living organisms. The content is more highly enriched in women than in men and can enter …

Cohort profile: the Dutch famine birth cohort (DFBC)—a prospective birth cohort study in the Netherlands

LS Bleker, SR de Rooij, RC Painter, ACJ Ravelli… - BMJ open, 2021 - bmjopen.bmj.com
Purpose The Dutch famine birth cohort study was set up to investigate the effects of acute
maternal undernutrition of the 1944–1945 Dutch famine during the specific stages of …

Epigenetics and the Developmental Origins of Health and Disease: Parental environment signalling to the epigenome, critical time windows and sculpting the adult …

S Safi-Stibler, A Gabory - Seminars in cell & developmental biology, 2020 - Elsevier
Abstract The literature about Developmental Origins of Health and Disease (DOHaD)
studies is considerably growing. Maternal and paternal environment, during all the …

[HTML][HTML] Transcriptomic profiling reveals differential cellular response to copper oxide nanoparticles and polystyrene nanoplastics in perfused human placenta

S Chortarea, G Gupta, LA Saarimäki… - Environment …, 2023 - Elsevier
The growing nanoparticulate pollution (eg engineered nanoparticles (NPs) or nanoplastics)
has been shown to pose potential threats to human health. In particular, sensitive …

Applying an evolutionary mismatch framework to understand disease susceptibility

AJ Lea, AG Clark, AW Dahl, O Devinsky, AR Garcia… - PLoS …, 2023 - journals.plos.org
Noncommunicable diseases (NCDs) are on the rise worldwide. Obesity, cardiovascular
disease, and type 2 diabetes are among a long list of “lifestyle” diseases that were rare …

The good, the bad, and the ugly of pregnancy nutrients and developmental programming of adult disease

CN Hsu, YL Tain - Nutrients, 2019 - mdpi.com
Maternal nutrition plays a decisive role in developmental programming of many non-
communicable diseases (NCDs). A variety of nutritional insults during gestation can cause …