The heterotrimeric G-protein alpha subunit has long been considered a bimodal, GTP-
hydrolyzing switch controlling the duration of signal transduction by seven-transmembrane …

The regulators of G-protein signaling (RGS) proteins were initially characterized as inhibitors
of signal transduction cascades initiated by G-protein-coupled receptors (GPCR) because of …

Regulators of G-protein signalling (RGS) proteins are a large and diverse family initially
identified as GTPase activating proteins (GAPs) of heterotrimeric G-protein Gα-subunits. At …

Regulators of G protein signaling (RGS) proteins modulate the physiologic actions of many
neurotransmitters, hormones, and other signaling molecules. Human RGS proteins …

G protein-coupled receptors (GPCRs) have important functions in both innate and adaptive
immunity, with the capacity to bridge interactions between the two arms of the host …

Signal transduction through G-protein–coupled receptors (GPCRs) is central for the
regulation of virtually all cellular functions and has been widely implicated in human …

Taste receptors (TASRs) are expressed not only in the oral cavity but also throughout the
body, thus suggesting that they may play different roles in organ systems beyond the tongue …

The regulators of G protein signaling (RGS) are a family of cellular proteins that play an
essential regulatory role in G protein-mediated signal transduction. There are multiple RGS …

Bitter taste receptors (TAS2RS) expression is not restricted to the oral cavity and the
presence of these receptors in the male reproductive system and sperm provides insights …

G protein-coupled receptor signaling mechanisms are implicated in many aspects of
cardiovascular control, and dysfunction of such signaling mechanisms is commonly …