This article reviews the pharmacokinetics of heroin after intravenous, oral, intranasal,
intramuscular and rectal application and after inhalation in humans, with a special focus on …

Background and aims This narrative review aims to provide a brief history of the
development of the heroin overdose field by discussing a selection of major 'classics' from …

Background For the past 30 years, opioids have been used to treat chronic nonmalignant
pain. This study tests the following hypotheses:(1) there is no strong evidence-based …

Aims To determine the contribution of heroin, prescription opioids, cocaine and alcohol/drug
combinations to the total overdose death rate and identify changes in drug overdose …

A simple, sensitive and selective electrochemical method was developed for the
simultaneous determination of morphine and codeine using a carbon paste electrode (CPE) …

Background and aims The feasibility of intervention in heroin overdose is of clinical
importance. The presence of 6‐monoacetyl morphine (6MAM) in the blood is suggestive of …

Aim To determine the total mortality related to the Stockholm methadone programme during
the period 1988–2000, both the mortality related to the treatment and fatal methadone …

Opioids are the most common drugs associated with unintentional drug overdose. Death
results from respiratory depression. Prolonged use of opioids results in the development of …

Opioids are respiratory depressants and heroin/opioid overdose is a major contributor to the
excess mortality of heroin addicts. The individual and situational variability of respiratory …

Heroin is a worldwide scourge and a seemingly intractable one. The Life of the Heroin User:
Typical Beginnings, Trajectories and Outcomes is the first book to apply a biographical …