Differential Treatment Effects of Subgroup Analyses in Phase 3 Oncology Trials From 2004 to 2020
Importance Subgroup analyses are often performed in oncology to investigate differential
treatment effects and may even constitute the basis for regulatory approvals. Current …
treatment effects and may even constitute the basis for regulatory approvals. Current …
Postprogression therapy and confounding for the estimated treatment effect on overall survival in phase III oncology trials
Objective Estimations of the treatment effect on overall survival (OS) may be influenced by
post-progression therapies (PPTs). It is unclear how often OS analyses account for PPT …
post-progression therapies (PPTs). It is unclear how often OS analyses account for PPT …
Based on the Real-World Results From Australia, Immunotherapy Is Not a Good Option for Patients With Mesothelioma
In recent years, the treatment paradigm for pleural mesothelioma (PM) has been expanded
after the development and rollout of immune checkpoint inhibitors (ICIs), 1 whereas the …
after the development and rollout of immune checkpoint inhibitors (ICIs), 1 whereas the …