Advancement in leishmaniasis diagnosis and therapeutics: An update

D Kumari, S Perveen, R Sharma, K Singh - European Journal of …, 2021 - Elsevier
Leishmaniasis is regarded as a neglected tropical disease by World Health Organization
(WHO) and is ranked next to malaria as the deadliest protozoan disease. The primary …

Laboratory diagnostics for human Leishmania infections: a polymerase chain reaction-focussed review of detection and identification methods

I Gow, NC Smith, D Stark, J Ellis - Parasites & Vectors, 2022 - Springer
Leishmania infections span a range of clinical syndromes and impact humans from many
geographic foci, but primarily the world's poorest regions. Transmitted by the bite of a female …

The pathogenicity and virulence of Leishmania-interplay of virulence factors with host defenses

AK Gupta, S Das, M Kamran, SA Ejazi, N Ali - Virulence, 2022 - Taylor & Francis
Leishmaniasis is a group of disease caused by the intracellular protozoan parasite of the
genus Leishmania. Infection by different species of Leishmania results in various host …

[HTML][HTML] Synthesis, spectroscopic characterization, antileishmanial, DNA binding, antioxidant, cytotoxicity, antifungal and antibacterial studies of organotin (IV) …

S Hussain, S Shujah, A Rehman, ST Hussain… - Arabian Journal of …, 2023 - Elsevier
Six new organotin (IV) complexes,[Bu 2 SnL](1),[Me 2 SnL](2),[Me 3 SnL](3),[Bu 3
SnL](4),[Ph 3 SnL](5) and [(n-Oct 2 SnL](6) have been synthesized from the reaction of 4-((5 …

Genetically modified live attenuated vaccine: a potential strategy to combat visceral leishmaniasis

SC Pandey, A Kumar, M Samant - Parasite Immunology, 2020 - Wiley Online Library
Visceral leishmaniasis (VL) is caused by a protozoan parasite Leishmania donovani mainly
influencing the population of tropical and subtropical regions across the globe. The arsenal …

Computational system level approaches for discerning reciprocal regulation of IL10 and IL12 in leishmaniasis

S Khandibharad, S Singh - Frontiers in Genetics, 2022 - frontiersin.org
IL12 and IL10 are two of the major cytokines which control the fate of Leishmaniasis. This
paper presents two models healthy state and diseased state which shows how secretion of …

[HTML][HTML] Cytokines and splenic remodelling during Leishmania donovani infection

MM de Oca, CR Engwerda, PM Kaye - Cytokine: X, 2020 - Elsevier
Visceral leishmaniasis (VL) causes extensive splenic pathology that contributes to
dysfunctional immune responses, in part through displacement and destruction of cell …

DDX3 DEAD-box RNA helicase (Hel67) gene disruption impairs infectivity of Leishmania donovani and induces protective immunity against visceral leishmaniasis

SC Pandey, V Pande, M Samant - Scientific reports, 2020 - nature.com
Visceral leishmaniasis (VL) is a vector-borne disease caused by the digenetic protozoan
parasite Leishmania donovani complex. So far there is no effective vaccine available …

Development and clinical evaluation of serum and urine-based lateral flow tests for diagnosis of human visceral leishmaniasis

SA Ejazi, ST Choudhury, A Bhattacharyya, M Kamran… - Microorganisms, 2021 - mdpi.com
Visceral leishmaniasis (VL), a fatal parasitic infection, is categorized as being neglected
among tropical diseases. The use of conventional tissue aspiration for diagnosis is not …

A Late Diagnosis of Visceral Leishmaniasis Using Tru-Cut Biopsy of the Spleen and Malaria Co-Infection–A Diagnostic Challenge: A Case Report in Somalia

MA Hassan, AA Omar, IA Mohamed… - Infection and Drug …, 2023 - Taylor & Francis
Background Visceral leishmaniasis (VL) is fatal neglected parasitic illness caused by
Leishmania donovani. The diagnosis remains a challenge due to the non-specific clinical …