Pharmacokinetic characterization, benefits and barriers of subcutaneous administration of monoclonal antibodies in oncology
A Homšek, J Spasić, N Nikolić… - Journal of Oncology …, 2023 - journals.sagepub.com
Objective Therapeutic monoclonal antibodies in oncology are slowly becoming the
dominant treatment option for many different cancer types. The main route of administration …
dominant treatment option for many different cancer types. The main route of administration …
Integrating Clopidogrel's First-Pass Effect in a Joint Semi-Physiological Population Pharmacokinetic Model of the Drug and Its Inactive Carboxylic Acid Metabolite
Z Pejčić, V Topić Vučenović, B Miljković, KM Vučićević - Pharmaceutics, 2024 - mdpi.com
Clopidogrel (CLO), a pro-drug for preventing thrombotic events, undergoes rapid absorption
and extensive metabolism, with approximately 85–90% converted to an inactive carboxylic …
and extensive metabolism, with approximately 85–90% converted to an inactive carboxylic …
Population Pharmacokinetic Model of Linezolid and Probability of Target Attainment in Patients with COVID-19-Associated Acute Respiratory Distress Syndrome on …
D Milaković, T Kovačević, P Kovačević, V Barišić… - Pharmaceutics, 2024 - mdpi.com
During veno-venous extracorporeal membrane oxygenation (vv ECMO) therapy,
antimicrobial drugs are frequently used, and appropriate dosing is challenging due to there …
antimicrobial drugs are frequently used, and appropriate dosing is challenging due to there …
Understanding hemoglobin contribution to high-dose methotrexate disposition—population pharmacokinetics in pediatric patients with hematological malignancies
B Škorić, M Jovanović, M Kuzmanović… - European Journal of …, 2024 - Springer
Purpose The aim of the present study was to develop a population pharmacokinetic model
for methotrexate (MTX) during high-dose treatment (HDMTX) in pediatric patients with acute …
for methotrexate (MTX) during high-dose treatment (HDMTX) in pediatric patients with acute …
[图书][B] PKPD-Model Based Preclinical Characterization of the Activity of Spectinamide 1599 Against Mycobacterial Subpopulations and the Identification of Potential …
ZH Temrikar - 2023 - search.proquest.com
Tuberculosis is one of the top 10 causes of death worldwide and the leading cause of death
from a single infectious agent prior to COVID19. Mycobacterium tuberculosis (Mtb) is the …
from a single infectious agent prior to COVID19. Mycobacterium tuberculosis (Mtb) is the …
PHARMACOMETRIC MODELS-A MODERN TOOL FOR QUANTIFYING VARIABILITY AND INDIVIDUALIZING DRUG DOSING REGIMENS
K Vučićević - Archives of Pharmacy, 2023 - aseestant.ceon.rs
Pharmacometric models are a powerful tool and an essential aspect of modern
pharmaceutical research, drug development and clinical practice. They provide a …
pharmaceutical research, drug development and clinical practice. They provide a …
[引用][C] Farmakometrijski modeli–savremen alat za kvantifikaciju varijabilnosti i individualizaciju režima doziranja lekova
K Vučićević - Arhiv za farmaciju, 2023 - Savez farmaceutskih udruženja …