ABSTRACT HIV-1 antiretroviral therapy management requires sequencing the protease,
reverse transcriptase, and integrase portions of the HIV-1 pol gene. Most resistance testing …

Background Viral resistance to antiretroviral therapy threatens our best methods to control
and prevent HIV infection. Current drug resistance genotyping methods are costly, optimized …

Over the past decade, there has been an increase in the adoption of next generation
sequencing (NGS) technologies for HIV drug resistance (HIVDR) testing. NGS far outweighs …

Resistance to antiretroviral therapy (ART) threatens the efficacy of human immunodeficiency
virus type 1 (HIV-1) treatment. We present a review of knowledge gaps in the science and …

Increased access to highly active antiretroviral therapy (HAART) by human
immunodeficiency virus postive (HIV+) individuals has become a reality worldwide. In Brazil …

HIV-1 entry into host cells is mediated by interactions between the V3-loop of viral
glycoprotein gp120 and chemokine receptor CCR5 or CXCR4, collectively known as HIV-1 …

Analysing the HIV-1 near full-length genome (HIV-NFLG) facilitates new understanding into
the diversity of virus population dynamics at individual or population level. In this study we …

Abstract Introduction In Mexico, HIV genotyping is performed in people living with HIV
(PLWH) failing their first-line antiretroviral (ARV) regimen; it is not routinely done for all …

Influenza virus represents a major public health concern worldwide after recent pandemics.
To aid the understanding and characterization of the virus in ever-increasing sample …

Background The current widely applied standard method to screen for HIV-1 genotypic
resistance is based on Sanger population sequencing (Sseq), which does not allow for the …