The review of alpha‐linolenic acid: Sources, metabolism, and pharmacology

Q Yuan, F Xie, W Huang, M Hu, Q Yan… - Phytotherapy …, 2022 - Wiley Online Library
α‐linolenic acid (ALA, 18: 3n‐3) is a carboxylic acid composed of 18 carbon atoms and three
cis double bonds, and is an essential fatty acid indispensable to the human body. This study …

[HTML][HTML] Impact of α-linolenic acid, the vegetable ω-3 fatty acid, on cardiovascular disease and cognition

A Sala-Vila, J Fleming, P Kris-Etherton, E Ros - Advances in Nutrition, 2022 - Elsevier
Given the evidence of the health benefits of plant-based diets and long-chain n–3 (ω-3) fatty
acids, there is keen interest in better understanding the role of α-linolenic acid (ALA), a plant …

Metabolism and functional effects of plant-derived omega-3 fatty acids in humans

EJ Baker, EA Miles, GC Burdge, P Yaqoob… - Progress in lipid …, 2016 - Elsevier
Alpha-linolenic acid (ALA) is an essential fatty acid and the substrate for the synthesis of
longer-chain, more unsaturated ω-3 fatty acids, eicosapentaenoic acid (EPA) …

Diabetes mellitus, blood glucose and the risk of atrial fibrillation: a systematic review and meta-analysis of cohort studies

D Aune, T Feng, S Schlesinger, I Janszky… - Journal of Diabetes and …, 2018 - Elsevier
Background Diabetes and elevated blood glucose have been associated with increased risk
of atrial fibrillation in a number of epidemiological studies, however, the findings have not …

Dietary fat and risk of cardiovascular disease: recent controversies and advances

DD Wang, FB Hu - Annual review of nutrition, 2017 - annualreviews.org
Health effects of dietary fats have been extensively studied for decades. However,
controversies exist on the effects of various types of fatty acids, especially saturated fatty acid …

α-Linolenic acid: Nutraceutical, pharmacological and toxicological evaluation

KB Kim, YA Nam, HS Kim, AW Hayes… - Food and chemical …, 2014 - Elsevier
Abstract α-Linolenic acid (ALA), a carboxylic acid with 18 carbons and three cis double
bonds, is an essential fatty acid needed for human health and can be acquired via regular …

[HTML][HTML] Health benefits of plant-derived α-linolenic acid

S Rajaram - The American journal of clinical nutrition, 2014 - Elsevier
ABSTRACT α-Linolenic acid (ALA) is an n–3 (ω-3) fatty acid found mostly in plant foods such
as flaxseed, walnuts, and vegetable oils, including canola and soybean oils. Most of the …

Indications for omega-3 long chain polyunsaturated fatty acid in the prevention and treatment of cardiovascular disease

P Nestel, P Clifton, D Colquhoun, M Noakes… - Heart, Lung and …, 2015 - Elsevier
Background The National Heart Foundation of Australia (NHFA) 2008 review on omega-3
long-chain polyunsaturated fatty acids (LCPUFA) made recommendations with respect to …

Serial circulating omega 3 polyunsaturated fatty acids and healthy ageing among older adults in the Cardiovascular Health Study: prospective cohort study

HTM Lai, MC de Oliveira Otto, RN Lemaitre… - bmj, 2018 - bmj.com
Objective To determine the longitudinal association between serial biomarker measures of
circulating omega 3 polyunsaturated fatty acid (n3-PUFA) levels and healthy ageing. Design …

Dietary patterns and components to prevent and treat heart failure: a comprehensive review of human studies

CP Kerley - Nutrition Research Reviews, 2019 - cambridge.org
Growing evidence has emerged about the role of dietary patterns and components in heart
failure (HF) incidence and severity. The objective here is to provide a comprehensive …