Impact of ZNF804A rs1344706 or CACNA1C rs1006737 polymorphisms on cognition in patients with severe mental disorders: A systematic review and meta …
AC Novaes de Oliveira Roldan… - The World Journal of …, 2023 - Taylor & Francis
Objectives This systematic review and meta-analysis focussed on insights into the
relationship between CACNA1C-rs1006737 and ZNF804A-rs1344706 polymorphisms and …
relationship between CACNA1C-rs1006737 and ZNF804A-rs1344706 polymorphisms and …
Region-specific expression of circular RNAs in the mouse brain
Circular RNAs (circRNAs) are abundant in mammalian brain and their expression is
regulated in a tissue-and developmental stage-specific manner. Mammalian brain is the …
regulated in a tissue-and developmental stage-specific manner. Mammalian brain is the …
[HTML][HTML] Differential H3K9me2 heterochromatin levels and concordant mRNA expression in postmortem brain tissue of individuals with schizophrenia, bipolar, and …
The existence of repressive and durable chromatin assemblies along gene promoters or
networks, especially in the brain, is of theoretical and therapeutic relevance in a subset of …
networks, especially in the brain, is of theoretical and therapeutic relevance in a subset of …
[HTML][HTML] A genome-wide association study and complex network identify four core hub genes in bipolar disorder
Z Xie, X Yang, X Deng, M Ma, K Shu - International Journal of Molecular …, 2017 - mdpi.com
Bipolar disorder is a common and severe mental illness with unsolved pathophysiology. A
genome-wide association study (GWAS) has been used to find a number of risk genes, but it …
genome-wide association study (GWAS) has been used to find a number of risk genes, but it …
[HTML][HTML] Identifying drug targets for schizophrenia through gene prioritization
Background: Schizophrenia genome-wide association studies (GWASes) have identified>
250 significant loci and prioritized> 100 disease-related genes. However, gene prioritization …
250 significant loci and prioritized> 100 disease-related genes. However, gene prioritization …
[HTML][HTML] Activation of the Akt/mTOR signaling pathway: a potential response to long-term neuronal loss in the hippocampus after sepsis
J Guo, L Tian, W Liu, J Mu, D Zhou - Neural Regeneration …, 2017 - journals.lww.com
Survivors of sepsis may suffer chronic cognitive impairment as a long-term sequela.
However, the precise mechanisms of cognitive dysfunction after sepsis are not well …
However, the precise mechanisms of cognitive dysfunction after sepsis are not well …
Multi-modal Spatial-modality Attentive Fusion for Studying Neuropsychiatric Disorders
Multi-modal learning has emerged as a powerful technique that leverages diverse data
sources to enhance learning and decision-making processes. Adapting this approach to …
sources to enhance learning and decision-making processes. Adapting this approach to …
Motor learning deficits and striatal GSK-3 hyperactivity in Akt3 knockout mice.
B Ouimet, É Pépin, Y Bergeron, L Chagniel… - Behavioral …, 2019 - psycnet.apa.org
Abstract Akt protein family (Akt1, Akt2 and Akt3) of serine/threonine kinases, also known as
protein kinase B, are enzymes implicated in many physiological and pathological processes …
protein kinase B, are enzymes implicated in many physiological and pathological processes …
WNKs regulate mouse behavior and alter central nervous system glucose uptake and insulin signaling
AB Jaykumar, D Binns, CA Taylor IV, A Anselmo… - bioRxiv, 2024 - biorxiv.org
Certain areas of the brain involved in episodic memory and behavior, such as the
hippocampus, express high levels of insulin receptors and glucose transporter-4 (GLUT4) …
hippocampus, express high levels of insulin receptors and glucose transporter-4 (GLUT4) …
Synergistic efficacy and diminished adverse effect profile of composite treatment of several ADHD medications
D Park, DFN Mabunga, KJ Adil, O Ryu, S Valencia… - …, 2021 - Elsevier
Although attention-deficit/hyperactivity disorder (ADHD) is widely studied, problems
regarding the adverse effect risks and non-responder problems still need to be addressed …
regarding the adverse effect risks and non-responder problems still need to be addressed …