Deciphering the Biosynthesis and Physiological Function of 5-Methylated Pyrazinones Produced by Myxobacteria
LL Zhu, Q Yang, DG Wang, L Niu, Z Pan, S Li… - ACS Central …, 2024 - ACS Publications
Myxobacteria are a prolific source of secondary metabolites with sheer chemical complexity,
intriguing biosynthetic enzymology, and diverse biological activities. In this study, we report …
intriguing biosynthetic enzymology, and diverse biological activities. In this study, we report …
Targeted sampling of natural product space to identify bioactive natural product-like polyketide macrolides
DM Wilson, DJ Driedger, DY Liu… - Nature …, 2024 - nature.com
Polyketide or polyketide-like macrolides (pMLs) continue to serve as a source of inspiration
for drug discovery. However, their inherent structural and stereochemical complexity …
for drug discovery. However, their inherent structural and stereochemical complexity …