Identifying Antisense Oligonucleotides to Disrupt Small RNA Regulated Antibiotic Resistance via a Cell-Free Transcription–Translation Platform
MJ Tsai, RAI Zambrano, JL Susas, L Silva… - ACS Synthetic …, 2023 - ACS Publications
Bacterial small RNAs (sRNAs) regulate many important physiological processes in cells,
including antibiotic resistance and virulence genes, through base-pairing interactions with …
including antibiotic resistance and virulence genes, through base-pairing interactions with …
[HTML][HTML] Small Noncoding RNAs and Their Role in the Pathogenesis of Mycobacterium tuberculosis Infection
AA Ostrik, TL Azhikina, EG Salina - Biochemistry (Moscow), 2021 - Springer
Mycobacterium tuberculosis possesses a significant arsenal of strategies to combat immune
defense of the host organism. Small noncoding RNAs, which constitute the largest group of …
defense of the host organism. Small noncoding RNAs, which constitute the largest group of …
Role of non-coding RNAs in tuberculosis and their potential for clinical applications
MI Jumat, ME Sarmiento, A Acosta… - Journal of applied …, 2023 - academic.oup.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains the leading cause
of mortality due to infectious diseases, only surpassed in 2020 by COVID-19. Despite the …
of mortality due to infectious diseases, only surpassed in 2020 by COVID-19. Despite the …
[HTML][HTML] The Acinetobacter baumannii model can explain the role of small non-coding RNAs as potential mediators of host-pathogen interactions
Bacterial small RNAs (sRNAs) research has accelerated over the past decade, boosted by
advances in RNA-seq technologies and methodologies for capturing both protein–RNA and …
advances in RNA-seq technologies and methodologies for capturing both protein–RNA and …
uORF‐mediated riboregulation controls transcription of whiB7/wblC antibiotic resistance gene
WhiB7/WblC is a transcriptional factor of actinomycetes conferring intrinsic resistance to
multiple translation‐inhibitory antibiotics. It positively autoregulates its own transcription in …
multiple translation‐inhibitory antibiotics. It positively autoregulates its own transcription in …
Drug resistance and gene transfer mechanisms in respiratory/oral bacteria
S Jiang, J Zeng, X Zhou, Y Li - Journal of Dental Research, 2018 - journals.sagepub.com
Growing evidence suggests the existence of new antibiotic resistance mechanisms. Recent
studies have revealed that quorum-quenching enzymes, such as MacQ, are involved in both …
studies have revealed that quorum-quenching enzymes, such as MacQ, are involved in both …
[HTML][HTML] Understanding Antimicrobial Resistance Using Genome-Scale Metabolic Modeling
T Alonso-Vásquez, M Fondi, E Perrin - Antibiotics, 2023 - mdpi.com
The urgent necessity to fight antimicrobial resistance is universally recognized. In the search
of new targets and strategies to face this global challenge, a promising approach resides in …
of new targets and strategies to face this global challenge, a promising approach resides in …
[HTML][HTML] Comparison of freeze-thaw and sonication cycle-based methods for extracting AMR-associated metabolites from Staphylococcus aureus
Emerging antimicrobial resistance (AMR) among Gram-positive pathogens, specifically in
Staphylococcus aureus (S. aureus), is becoming a leading public health concern …
Staphylococcus aureus (S. aureus), is becoming a leading public health concern …
[HTML][HTML] microRNAs associated with the pathogenesis and their role in regulating various signaling pathways during Mycobacterium tuberculosis infection
KS Davuluri, DS Chauhan - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Despite more than a decade of active study, tuberculosis (TB) remains a serious health
concern across the world, and it is still the biggest cause of mortality in the human …
concern across the world, and it is still the biggest cause of mortality in the human …
[HTML][HTML] Regulation of the macrolide resistance ABC-F translation factor MsrD
CR Fostier, F Ousalem, EC Leroy, S Ngo… - Nature …, 2023 - nature.com
A ntibiotic r esistance ABC-Fs (ARE ABC-Fs) are translation factors that provide resistance
against clinically important ribosome-targeting antibiotics which are proliferating among …
against clinically important ribosome-targeting antibiotics which are proliferating among …