[HTML][HTML] Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021 - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

[HTML][HTML] Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury

M Hanscom, DJ Loane… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …

[PDF][PDF] The IL-17 family of cytokines in health and disease

MJ McGeachy, DJ Cua, SL Gaffen - Immunity, 2019 - cell.com
The interleukin 17 (IL-17) family of cytokines contains 6 structurally related cytokines, IL-17A
through IL-17F. IL-17A, the prototypical member of this family, just passed the 25 th …

[PDF][PDF] Repopulating microglia promote brain repair in an IL-6-dependent manner

EF Willis, KPA MacDonald, QH Nguyen, AL Garrido… - Cell, 2020 - cell.com
Cognitive dysfunction and reactive microglia are hallmarks of traumatic brain injury (TBI), yet
whether these cells contribute to cognitive deficits and secondary inflammatory pathology …

[HTML][HTML] Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury

H Wu, J Zheng, S Xu, Y Fang, Y Wu, J Zeng… - Journal of …, 2021 - Springer
Background Traumatic brain injury (TBI) is a leading cause of death and disability
worldwide. Microglial/macrophage activation and neuroinflammation are key cellular events …

[HTML][HTML] Traumatic brain injury: mechanisms of glial response

RG Mira, M Lira, W Cerpa - Frontiers in physiology, 2021 - frontiersin.org
Traumatic brain injury (TBI) is a heterogeneous disorder that involves brain damage due to
external forces. TBI is the main factor of death and morbidity in young males with a high …

[PDF][PDF] Neuroimmunology of traumatic brain injury: time for a paradigm shift

YN Jassam, S Izzy, M Whalen, DB McGavern… - Neuron, 2017 - cell.com
Traumatic brain injury (TBI) is a leading cause of morbidity and disability, with a
considerable socioeconomic burden. Heterogeneity of pathoanatomical subtypes and …

[HTML][HTML] Catalytically potent and selective clusterzymes for modulation of neuroinflammation through single-atom substitutions

H Liu, Y Li, S Sun, Q Xin, S Liu, X Mu, X Yuan… - Nature …, 2021 - nature.com
Emerging artificial enzymes with reprogrammed and augmented catalytic activity and
substrate selectivity have long been pursued with sustained efforts. The majority of current …

[HTML][HTML] Pathophysiology and treatment of cerebral edema in traumatic brain injury

RM Jha, PM Kochanek, JM Simard - Neuropharmacology, 2019 - Elsevier
Cerebral edema (CE) and resultant intracranial hypertension are associated with
unfavorable prognosis in traumatic brain injury (TBI). CE is a leading cause of in-hospital …

The dialogue between neuroinflammation and adult neurogenesis: mechanisms involved and alterations in neurological diseases

M Amanollahi, M Jameie, A Heidari, N Rezaei - Molecular neurobiology, 2023 - Springer
Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …