The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments
MC Morganti-Kossmann, BD Semple, SC Hellewell… - Acta …, 2019 - Springer
This review recounts the definitions and research evidence supporting the multifaceted roles
of neuroinflammation in the injured brain following trauma. We summarise the literature …
of neuroinflammation in the injured brain following trauma. We summarise the literature …
[HTML][HTML] Molecular mechanisms underlying neuroinflammation elicited by occupational injuries and toxicants
D Pathak, K Sriram - International Journal of Molecular Sciences, 2023 - mdpi.com
Occupational injuries and toxicant exposures lead to the development of neuroinflammation
by activating distinct mechanistic signaling cascades that ultimately culminate in the …
by activating distinct mechanistic signaling cascades that ultimately culminate in the …
[HTML][HTML] Neuroinflammation following traumatic brain injury: take it seriously or not
R Zheng, K Lee, Z Qi, Z Wang, Z Xu, X Wu… - Frontiers in …, 2022 - frontiersin.org
Traumatic brain injury (TBI) is associated with high mortality and disability, with a substantial
socioeconomic burden. With the standardization of the treatment process, there is increasing …
socioeconomic burden. With the standardization of the treatment process, there is increasing …
[HTML][HTML] Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury
H Wang, XM Zhou, LY Wu, GJ Liu, WD Xu… - Journal of …, 2020 - Springer
Abstract Background Aucubin (Au), an iridoid glycoside from natural plants, has
antioxidative and anti-inflammatory bioactivities; however, its effects on a traumatic brain …
antioxidative and anti-inflammatory bioactivities; however, its effects on a traumatic brain …
[HTML][HTML] Military traumatic brain injury: a challenge straddling neurology and psychiatry
LZ Kong, RL Zhang, SH Hu, JB Lai - Military medical research, 2022 - Springer
Military psychiatry, a new subcategory of psychiatry, has become an invaluable, intangible
effect of the war. In this review, we begin by examining related military research …
effect of the war. In this review, we begin by examining related military research …
Selective NLRP3 inflammasome inhibitor reduces neuroinflammation and improves long-term neurological outcomes in a murine model of traumatic brain injury
The nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain
containing 3 (NLRP3) inflammasome-mediated inflammatory response has emerged as a …
containing 3 (NLRP3) inflammasome-mediated inflammatory response has emerged as a …
[HTML][HTML] Engineered nanomaterials that exploit blood-brain barrier dysfunction for delivery to the brain
The blood–brain barrier (BBB) is a highly regulated physical and functional boundary that
tightly controls the transport of materials between the blood and the brain. There is an …
tightly controls the transport of materials between the blood and the brain. There is an …
A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury
X Zhao, W Zeng, H Xu, Z Sun, Y Hu, B Peng… - Science translational …, 2023 - science.org
Tau pathogenesis is a hallmark of many neurodegenerative diseases, including Alzheimer's
disease (AD). Although the events leading to initial tau misfolding and subsequent tau …
disease (AD). Although the events leading to initial tau misfolding and subsequent tau …
Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway
J Wang, C Jiang, K Zhang, X Lan, X Chen… - Free radical biology and …, 2019 - Elsevier
Traumatic brain injury (TBI) is a principal cause of death and disability worldwide. Melatonin,
a hormone made by the pineal gland, is known to have anti-inflammatory and antioxidant …
a hormone made by the pineal gland, is known to have anti-inflammatory and antioxidant …
Carbogenic nanozyme with ultrahigh reactive nitrogen species selectivity for traumatic brain injury
Reactive oxygen and nitrogen species (RONS), especially reactive nitrogen species (RNS)
are intermediate products during incidence of nervous system diseases, showing …
are intermediate products during incidence of nervous system diseases, showing …