Cancer genetics is increasingly becoming integrated into the practice of modern medical
oncology. The ability to distinguish a growing proportion of the 5% to 10% of all cancers that …

DEVELOPMENT OF treatment guidelines for early breast cancer requires comprehensive
analysis of the results of randomized clinical trials and the interpretation of their biologic …

The excess risk of second malignancy after Hodgkin disease is an increasing problem. In
light of the long-term data, guidelines for follow-up of survivors of Hodgkin disease need to …

This multi-centre UK study assesses the impact of predictive testing for breast and ovarian
cancer predisposition genes (BRCA1/2) in the clinical context. In the year following …

Purpose: To analyze the use of genetic testing, prophylactic mastectomy, and oophorectomy
among women with breast and/or ovarian cancer from families with a BRCA1 or BRCA2 …

Dedicated clinics have been established for the early diagnosis and treatment of women at
risk for inherited breast cancer, but the effects of such interventions are currently unproven …

The aim of this multi-centre UK study is to examine the attributes of a cohort offered
predictive genetic testing for breast/ovarian cancer predisposition. Participants are adults …

Over the past two decades, molecular technologies have transformed the landscape of
cancer diagnosis, treatment and disease surveillance. However, although the effects of …

Background Breast cancer (BC) detection in women with a genetic susceptibility or strong
family history is considered mandatory compared with BC screening in the general …

Despite there being an increasing literature on the impact of cancer genetic counseling on
risk perception and mental health, there is a lack of data describing impact on risk …