Anesthesia and analgesia for common research models of adult mice

S Ahmadi-Noorbakhsh, M Farajli Abbasi… - Laboratory animal …, 2022 - Springer
Anesthesia and analgesia are major components of many interventional studies on
laboratory animals. However, various studies have shown improper reporting or use of …

Cardiovascular magnetic resonance imaging for sequential assessment of cardiac fibrosis in mice: technical advancements and reverse translation

YC Chen, G Zheng, DG Donner… - American Journal …, 2024 - journals.physiology.org
Cardiovascular magnetic resonance (CMR) imaging has become an essential technique for
the assessment of cardiac function and morphology, and is now routinely used to monitor …

Optogenetic stimulation of anterior insular cortex neurons in male rats reveals causal mechanisms underlying suppression of the default mode network by the salience …

V Menon, D Cerri, B Lee, R Yuan, SH Lee… - Nature …, 2023 - nature.com
The salience network (SN) and default mode network (DMN) play a crucial role in cognitive
function. The SN, anchored in the anterior insular cortex (AI), has been hypothesized to …

Cardiac electrophysiology studies in mice via the transjugular route: a comprehensive practical guide

K Favere, J Van Fraeyenhove… - American Journal …, 2022 - journals.physiology.org
Cardiac arrhythmias are associated with cardiovascular morbidity and mortality. Cardiac
electrophysiology studies (EPS) use intracardiac catheter recording and stimulation for …

Unmasking the adverse impacts of sex bias on science and research animal welfare

EA Nunamaker, PV Turner - Animals, 2023 - mdpi.com
Simple Summary Sex bias—the use of one sex over the other—is a common practice in
biomedical research, typically with over selection of male animals. There are a number of …

Automated measurement of distance-walked as a “sixth vital sign” for detecting infusion reactions during preclinical testing

LS Chase, MH Zaleski, LJ Morrell… - International Journal of …, 2023 - Elsevier
Infusion reactions are a major risk for advanced therapeutics (eg, engineered proteins
nanoparticles, etc.), which can trigger the complement cascade, anaphylaxis, and other life …

Opioid overdose detection in a murine model using a custom-designed Photoplethysmography device

OS Hoilett, JD Ummel, LE Schepers, AH Soepriatna… - IRBM, 2023 - Elsevier
Abstract Background and Objective Over 68,000 opioid-overdose related deaths occurred
within the United States in 2020 alone, indicating a need to develop technologies to help …

3D Optical Coherence Thermometry Using Polymeric Nanogels

T Muñoz‐Ortiz, I Alayeto, J Lifante… - Advanced …, 2023 - Wiley Online Library
In nanothermometry, the use of nanoparticles as thermal probes enables remote and
minimally invasive sensing. In the biomedical context, nanothermometry has emerged as a …

A protocol and a data-based prediction to investigate virus spillover at the wildlife interface in human-dominated and protected habitats in Thailand: The Spillover …

C Thinphovong, E Nordstrom-Schuler, P Soisook… - Plos one, 2024 - journals.plos.org
The Spillover Interface Project aims at assessing the encounter of wildlife, domestic animals,
and humans along a landscape gradient from a protected area to a residential community …

Lipopolysaccharide-initiated rhinosinusitis causes neuroinflammation and olfactory dysfunction in mice

CF Yeh, WH Huang, MY Lan… - American Journal of …, 2023 - journals.sagepub.com
Background Olfactory dysfunction is a common disease and it may be caused by sinonasal
inflammation, toxin inhalation, or neurological disorders. After sinonasal inflammation, if both …