Tuberculosis (TB), especially in developing countries, is a major threat to human health. The
pathogenesis of TB remains poorly understood, and< 5%–10% of individuals infected with …

The next wave of asthma genetic studies will use full-genome sequencing and overcome
most GWAS-associated problems. It will be the last step of a century-long search for asthma …

An association study was conducted to investigate the relation between 14 variants of
glucose transporter 1 gene (SLC2A1) and the risk of type 2 diabetes (T2DM) leading to …

Addictive behaviors, such as substance misuse, gambling, and internet gaming, and their
attendant problems are associated with significant difficulties for individuals, families …

Asthma exacerbation (AE) usually denotes worsening of asthma symptoms that requires
intense management to prevent further deterioration. AE has been reported to correlate with …

Tobacco smoking has been considered the most important risk factor for chronic obstructive
pulmonary disease (COPD) development. However, not all smokers develop COPD and …

Genome-wide association studies (GWAS) have discovered 163 loci related to coronary
heart disease (CHD). Most GWAS have emphasized pathways related to single-nucleotide …

It is becoming increasingly evident that the underlying mutation of a single locus is often
insufficient for the prediction of the comprehensive phenotype in human Mendelian …

ADP ribosylation factor like protein 15 (ARL15) was identified as a novel susceptibility gene
for rheumatoid arthritis (RA) based on a genomewide association study in a north Indian …

Objectives The available evidence from the genetic association studies (GAS) published to
date on the association between variants in the GABRA2 gene and alcoholism has …