Gamma-aminobutyric acid A receptor, α-2 (GABRA2) variants as individual markers for alcoholism: a meta-analysis

E Zintzaras - Psychiatric genetics, 2012 - journals.lww.com
Objectives The available evidence from the genetic association studies (GAS) published to
date on the association between variants in the GABRA2 gene and alcoholism has …

Correlation between an intronic SNP genotype and ARL15 level in rheumatoid arthritis

AK Pandey, A Saxena, SK Dey, M Kanjilal, U Kumar… - Journal of genetics, 2021 - Springer
ADP ribosylation factor like protein 15 (ARL15) was identified as a novel susceptibility gene
for rheumatoid arthritis (RA) based on a genomewide association study in a north Indian …

[HTML][HTML] Hidden hypotheses in 'hypothesis-free'genome-wide epigenetic associations

ED Barker, S Roberts, E Walton - Current Opinion in Psychology, 2019 - Elsevier
The recent interest in epigenetics within mental health research, from a developmental
perspective, stems from the potential of DNA methylation to index both exposure to adversity …

Discovery of complex pathways from observational data

JW Baurley, DV Conti, WJ Gauderman… - Statistics in …, 2010 - Wiley Online Library
Unraveling complex interactions has been a challenge in epidemiologic research. We
introduce a pathway modeling framework that discovers plausible pathways from …

Genetic insights into juvenile idiopathic arthritis derived from deep whole genome sequencing

L Wong, K Jiang, Y Chen, JN Jarvis - Scientific reports, 2017 - nature.com
Deep whole genome sequencing (WGS) allows for the comprehensive study of genetic
landscapes at finer resolution than array based methods. We conducted deep WGS on …

Polymorphisms of the endothelial nitric oxide synthase (NOS3) gene in preeclampsia: a candidate-gene association study

N Zdoukopoulos, C Doxani, IE Messinis… - BMC Pregnancy and …, 2011 - Springer
Background The endothelial nitric oxide synthase gene (NOS3) has been proposed as a
candidate gene for preeclampsia. However, studies so far have produced conflicting results …

SLC2A1 tag SNPs in Greek patients with diabetic retinopathy and nephropathy

V Siokas, A Fotiadou, E Dardiotis, MG Kotoula… - Ophthalmic …, 2019 - karger.com
Backround: Genetic variants are implicated in the development of diabetic retinopathy (DR)
and nephropathy (DN). The role of solute carrier family 2-facilitated glucose transporter …

Personalised medicine: the odyssey from hope to practice

S Visvikis-Siest, V Gorenjak… - Journal of personalized …, 2018 - mdpi.com
In this endeavour, inspired by the Odyssey, we aim to embark with the reader on a journey
on a ship from Troy to Ithaca, coursing through the history of the momentous events and …

An NOS3 Haplotype is Protective against Hypertension in a Caucasian Population

GD Kitsios, E Zintzaras - International journal of hypertension, 2010 - Wiley Online Library
The endothelial nitric oxide synthase gene (NOS3) has been implicated in the development
of hypertension, although the specific role of variants and haplotypes has not been clarified …

'OMICS-based'biomarkers for environmental health studies

A Espín-Pérez, J Krauskopf, TM de Kok… - Current Environmental …, 2014 - Springer
The development of biomarkers based on high-throughput techniques, cutting-edge
biostatistics and bioinformatics tools is revolutionizing molecular cancer epidemiology. Once …