Thermal activation of Argonaute nuclease enables one-pot multiplex detection of viruses
X Ye, Z Li, Z Fang, N Shen, Y Zhou, P Sun, H Xu… - Sensors and Actuators B …, 2024 - Elsevier
Advances in programmable nucleases such as CRISPR-associated proteins (Cas) and
Argonaute (Ago), combined with isothermal amplification, have made point-of-care testing …
Argonaute (Ago), combined with isothermal amplification, have made point-of-care testing …
Exploring the Frozen Armory: Antiphage Defense Systems in Cold-Adapted Bacteria with a Focus on CRISPR-Cas Systems
GD Sandsdalen, A Kumar, E Hjerde - Microorganisms, 2024 - mdpi.com
Our understanding of the antiphage defense system arsenal in bacteria is rapidly
expanding, but little is known about its occurrence in cold-adapted bacteria. In this study, we …
expanding, but little is known about its occurrence in cold-adapted bacteria. In this study, we …
Conditional Protein Denoising Diffusion Generates Programmable Endonucleases
Computation or deep learning-based functional protein generation methods address the
urgent demand for novel biocatalysts, allowing for precise tailoring of functionalities to meet …
urgent demand for novel biocatalysts, allowing for precise tailoring of functionalities to meet …
One-pot virus detection based on isothermal amplification coupled with temperature-activated argonaute
X Ye, Z Li, Z Fang, N Shen, Y Zhou, P Sun, H Xu, Q Liu… - bioRxiv, 2023 - biorxiv.org
Advances in programmable nucleases like CRISPR-associated protein (Cas) and
Argonaute (Ago), combined with isothermal amplification, have made point-of-care testing …
Argonaute (Ago), combined with isothermal amplification, have made point-of-care testing …
Structural and biochemical studies of an Argonaute and its associated protein from Archaeoglobus fulgidus
E Golovinas - 2024 - epublications.vu.lt
Abstract [eng] Argonaute (Ago) proteins, the key components of RNA interference (RNAi)
machinery, are ubiquitous across all domains of life. While eukaryotic Argonautes (eAgos) …
machinery, are ubiquitous across all domains of life. While eukaryotic Argonautes (eAgos) …